中国当代医药2026,Vol.33Issue(15):83-87,5.DOI:10.3969/j.issn.1674-4721.2026.15.18
中性粒细胞-淋巴细胞比值、降钙素原联合检测对儿童重症呼吸道合胞病毒肺炎的预测价值
Predictive value of combined detection of neutrophil-to-lymphocyte ratio and procalcitonin for severe respiratory syncytial virus pneumonia in children
摘要
Abstract
Objective To analyze the predictive value of combined detection of neutrophil-to-lymphocyte ratio(NLCR)and procalcitonin(PCT)for severe respiratory syncytial virus(RSV)pneumonia in children.Methods A total of 100 children with RSV pneumonia who were treated at Jiujiang Maternal and Child Health Hospital from March 2023 to January 2025 were selected as the research subjects.They were divided into the severe RSV pneumonia group(severe group,50 cases)and the non-severe RSV pneumonia group(non-severe group,50 cases)according to the diagnostic criteria for severe pneumo-nia.Within 24 h of admission,the lymphocyte count,neutrophil count,white blood cell count,and PCT level of the two groups of children were measured,and the NLCR level were calculated.The laboratory indicators,clinical characteristics(clinical manifestations,imaging manifestations)of the severe group and the non-severe group,as well as the predictive efficacy indicators of the combined detection of NLCR and PCT were analyzed.Results The lymphocyte count level of the severe group was lower than that of the non-severe group,while the neutrophil count,white blood cell count,PCT,and NLCR levels were higher than those of the non-severe group,and the differences were statistically significant(P<0.05).The secondary clinical manifestations and the proportion of atelectasis in the severe group were higher than those in the non-severe group,and the differences were statistically significant(P<0.05).The sensitivity and specificity of combined detection of PCT and NLCR for diagnosing severe RSV pneumonia were higher than those of detecting PCT or NLCR alone.Conclusion The combined detection of PCT and NLCR levels can more accurately identify the risk of severe deterioration in children with RSV infection and has a good predictive value for severe RSV pneumonia in children.关键词
中性粒细胞-淋巴细胞比值/降钙素原/儿童/重症/呼吸道合胞病毒肺炎Key words
Neutrophil-to-lymphocyte ratio/Procalcitonin/Children/Severe/Respiratory syncytial virus pneumonia分类
医药卫生引用本文复制引用
杨帆,刘洋..中性粒细胞-淋巴细胞比值、降钙素原联合检测对儿童重症呼吸道合胞病毒肺炎的预测价值[J].中国当代医药,2026,33(15):83-87,5.基金项目
江西省卫生健康委科技计划项目(202140347). (202140347)