实用心电与临床诊疗2026，Vol.35Issue(3)：400-406,7.DOI:10.13308/j.issn.2097-5716.xd20250411
不同根管内消毒方案联合生物陶瓷材料iRoot SP糊剂填充治疗急性根尖周炎的效果
Efficacy of different intracanal disinfection protocols combined with bioceramic material iRoot SP paste for obturation in treating acute apical periodontitis
摘要
Abstract
Objective To compare and observe the efficacy of different intracanal disinfection protocols combined with bioceramic material iRoot SP paste for root canal obturation in the treatment of acute apical periodontitis.Methods Clinical data of patients with acute apical periodontitis were collected for a retrospective study.According to different intracanal disinfection protocols,these patients were divided into a calcium hydroxide group and a triple antibiotic paste(TAP)group.To eliminate selection bias and ensure baseline comparability between the two groups,propensity score matching method was performed at a 1∶1 ratio,with matching variables including age,sex,and affected tooth position.After matching,119 patients were successfully included in each group.In the calcium hydroxide group,root canal filling with iRoot SP paste combined with intracanal disinfection using calcium hydroxide paste was applied,while in the TAP group,root canal filling with iRoot SP paste combined with intracanal disinfection using TAP was applied.Therapeutic effects,as well as preoperative and postoperative pain degrees[visual analogue scale(VAS)and masticatory function score],gingival crevicular fluid inflammatory factors[C-reactive protein(CRP),interleukin-8(IL-8)and tumor necrosis factor-α(TNF-α)],and periodontal indicators[periodontal pocket depth(PD),sulcus bleeding index(SBI)and gingival index(GI)]were compared between the two groups.The incidence of adverse reactions was also recorded.Results The total effective rate in the TAP group was higher than that in the calcium hydroxide group(96.64％vs.84.87％,P＜0.05).At 1 week and 3 months postoperatively,the TAP group showed lower VAS scores,higher masticatory function scores,and lower levels of CRP,IL-8 and TNF-α in gingival crevicular fluid,as well as lower PD,SBI and GI compared with the calcium hydroxide group(all P＜0.05).There was no statistically significant difference in the total incidence of adverse reactions between the TAP group(3.36％)and the calcium hydroxide group(7.56％,P＞0.05).Conclusion Compared with calcium hydroxide,the use of TAP for intracanal disinfection combined with iRoot SP for obturation in the treatment of acute apical periodontitis proves to be more effective in controlling inflammatory and improving clinical symptoms in the short term.关键词
急性根尖周炎/抗生素糊剂/疼痛/牙周指标/不良反应Key words
acute periapical periodontitis/antibiotic paste/pain/periodontal indicator/adverse reaction分类
医药卫生引用本文复制引用
闫胜男,李冬,徐娟娟,闫利辉..不同根管内消毒方案联合生物陶瓷材料iRoot SP糊剂填充治疗急性根尖周炎的效果[J].实用心电与临床诊疗,2026,35(3):400-406,7.基金项目
河南省医学教育研究项目(WJLX2024106) （WJLX2024106）
