兰州大学学报（医学版）2026，Vol.52Issue(4)：91-97,7.DOI:10.13885/j.issn.2097-681X.M20252190
银纳米改性口腔修复材料的抗菌性能及生物安全性挑战
Antibacterial performance and biosafety challenges of nano-silver modified dental restorative materials
摘要
Abstract
Oral bacterial infections serve as primary etiological factors for dental caries and periodontal diseases.Conventional restorative materials,due to their lack of active antimicrobial properties,often lead to secondary caries and peri-implantitis.Silver nanoparticles exhibit broad-spectrum antimicrobial activity,sus-tained-release properties and low resistance induction,demonstrating significant potential for enhancing the antibacterial performance of materials.This review summarized the modification strategies,antibacterial mechanisms and biosafety challenges associated with silver nanoparticles in both dental implant restorative materials and resin restorative materials,aiming to provide a reference for developing novel restorative materi-als that integrate effective antibacterial properties with biosafety.关键词
银纳米颗粒/口腔修复材料/抗菌性/生物安全性/二氧化钛/氧化锆/复合树脂/义齿基托Key words
silver nanoparticles/dental restorative materials/antibacterial activity/biosafety/titanium diox-ide/zirconium dioxide/composite resin/denture base分类
医药卫生引用本文复制引用
王琳,王龙玉,郑银琴,马秀云,朱涛..银纳米改性口腔修复材料的抗菌性能及生物安全性挑战[J].兰州大学学报（医学版）,2026,52(4):91-97,7.基金项目
甘肃省自然科学基金资助项目(23JRRA1000) （23JRRA1000）
甘肃省知识产权战略与政策研究项目(24ZSCQG002) （24ZSCQG002）
