环境与职业医学2026，Vol.43Issue(6)：778-785,8.DOI:10.11836/JEOM25500
颗粒物与噪声联合暴露对认知功能影响研究进展
Advances on effects of combined exposure to particulate matter and noise on cognitive function
卫怡君 1黄哲宇 1何丽华 1王云1
作者信息
- 1. 北京大学公共卫生学院劳动卫生与环境卫生学系,北京 100191
- 折叠
摘要
Abstract
With the accelerated global population aging and urbanization,cognitive dysfunction has become a major public health challenge.Epidemiological evidence indicates that long-term ex-posure to particulate matter and environmental noise are independent risk factors for cognitive decline,and recent studies suggest that their combined exposure may exert a synergistic ampli-fying effect.This review summarized the progress in epidemiological research on the impacts of particulate matter and noise exposure on cognitive function,specifically focusing on the synergistic effects of their combined exposure.Furthermore,it outlined common biological mechanisms such as neuroinflammation,oxidative stress,and vascular endothelial damage.However,while existing studies have preliminarily revealed the synergistic effects of combined particulate matter and noise exposure on cognitive function,the conclusions remain heterogeneous,and the inves-tigation of underlying mechanisms is still insufficient.Future research should prioritize refined exposure assessment,long-term cohort studies,and specific high-exposure occupational scenar-ios,and carry out further in-depth investigations,thereby providing a basis for health risk assess-ment and the development of intervention strategies.关键词
认知功能/颗粒物/噪声/联合暴露/环境暴露Key words
cognitive function/particulate matter/noise/combined exposure/environmental ex-posure分类
医药卫生引用本文复制引用
卫怡君,黄哲宇,何丽华,王云..颗粒物与噪声联合暴露对认知功能影响研究进展[J].环境与职业医学,2026,43(6):778-785,8.
