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白内障术后干眼的神经免疫机制及围手术期防治策略

王雪娇 俞方良

国际眼科杂志2026,Vol.26Issue(7):1185-1191,7.
国际眼科杂志2026,Vol.26Issue(7):1185-1191,7.DOI:10.3980/j.issn.1672-5123.2026.7.13

白内障术后干眼的神经免疫机制及围手术期防治策略

Neuroimmune mechanisms and perioperative management strategies for post-cataract surgery dry eye

王雪娇 1俞方良1

作者信息

  • 1. (330006)中国江西省南昌市,南昌大学附属眼科医院||(330006)中国江西省南昌市,南昌大学
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摘要

Abstract

·Post-cataract surgery dry eye(PCSDE)is a common complication,with an incidence of 9.2%-72.6%,and approximately 20%of patients experience persistent long-term symptoms.In the era of refractive cataract surgery,dry eye has become a critical factor affecting surgical satisfaction due to rising patient expectations for visual quality.Emerging evidence highlights that the interplay between neurosensory abnormalities and immune-inflammatory responses drives PCSDE chronicity,with psychoneurological factors gaining increasing attention.This review systematically examines PCSDE pathogenesis and contributing factors from this novel perspective,including surgical variables(incision design,operative duration,techniques),patient-related factors(age,meibomian gland function,systemic diseases,psychological status),and perioperative management(drug toxicity,disinfectant use).Additionally,based on the latest clinical evidence,comprehensive prevention and treatment strategies including preoperative optimization of ocular surface conditions,intraoperative ocular surface protection techniques,and personalized postoperative regimens are summarized.A deeper understanding of the multifactorial mechanisms of PCSDE is crucial for enhancing the quality of cataract surgery and improving patient outcomes.This review establishes a novel framework for PCSDE management based on neuro-immune-psychological interactions,offering crucial theoretical updates and practical guidance to enhance visual quality and patient satisfaction in refractive cataract surgery.

关键词

白内障术后干眼/手术源性干眼/神经免疫调节/心理因素/睑板腺功能障碍/围手术期管理

Key words

post-cataract surgery dry eye/surgery-induced dry eye/neuroimmune modulation/psychological factors/meibomian gland dysfunction/perioperative management

引用本文复制引用

王雪娇,俞方良..白内障术后干眼的神经免疫机制及围手术期防治策略[J].国际眼科杂志,2026,26(7):1185-1191,7.

国际眼科杂志

1672-5123

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