肿瘤预防与治疗2026，Vol.39Issue(6)：430-437,8.DOI:10.3969/j.issn.1674-0904.2026.06.002
多发性骨髓瘤患者生命质量测定量表之特异模块研制的条目筛选
Item Screening in Development of Specific Module of Quality of Life Scale for Multiple Myeloma Patients
摘要
Abstract
Objective:Currently,there is a lack of appropriate quality-of-life assessment tools for patients with multiple myeloma(MM)in China.This study aimed to devel-op the disease-specific module of the Quality of Life Instru-ments for Patients with MM(QLICP-MM),based on the Quality of Life Instruments for Cancer Patients-General Module(Version 2.0)(QLICP-GM V2.0).Methods:Using QLICP-GM V2.0 as the basic framework,this study adopted a com-bined approach of a general module and a disease-specific module.An initial item pool was generated through topic-group dis-cussions,followed by several rounds of core-group reviews to develop the preliminary scale.A total of 30 patients with MM and 20 medical professionals participated in questionnaires and interviews.Item screening was performed using the variation meth-od,correlation coefficient method,Cronbach's α method,and clinician-patient importance rating method.Screening thresh-olds were set as follows:correlation coefficient>0.50,coefficient of variation>0.90,no increase in Cronbach's α after item deletion,patient importance score≥70 points,and medical staff importance score≥80 points.Results:A total of 16 candi-date items were included in the analysis.The coefficient of variation for each item ranged from 0.85 to 1.60;item-dimension correlation coefficients ranged from 0.24 to 0.78.Cronbach's α remained stable(0.84～0.87)after item deletion.Patient importance scores ranged from 65.33 to 90.33,and medical professional importance scores ranged from 77.50 to 92.50.Based on the statistical results,10 items were retained.After expert consultation,11 items were finalized for the test version of the QLICP-MM disease-specific module.Conclusion:Using a rigorous process combining qualitative and small-sample quantitative methods,this study developed the disease-specific module of QLICP-MM.The final 11 items show good content validity and in-ternal consistency,laying a foundation for the future development of the formal scale and its clinical validation.关键词
多发性骨髓瘤/生命质量/特异性模块/条目筛选/量表研制Key words
Multiple myeloma/Quality of life/Specific module/Item screening/Scale development分类
医药卫生引用本文复制引用
余双,李伟强,谭健烽,孟琼,李高峰,万崇华..多发性骨髓瘤患者生命质量测定量表之特异模块研制的条目筛选[J].肿瘤预防与治疗,2026,39(6):430-437,8.基金项目
This study was supported by the National Natural Science Foundation of China(No.71974040,No.81273185). 国家自然科学基金(编号:71974040,81273185) （No.71974040,No.81273185）
