山西中医药大学学报2026，Vol.27Issue(6)：610-615,6.DOI:10.19763/j.cnki.2096-7403.2026.06.19
基于数据挖掘技术探讨查安生教授治疗胃食管反流病用药规律
Exploration of Professor Zha Ansheng's medication rules in treating gastroesophageal reflux disease based on data mining technology
摘要
Abstract
Objective:To explore medication compatibility rules of Professor Zha Ansheng's prescription in treating gastroesophageal reflux disease(GERD)using data mining technology,providing prescription basis and clinical insights for the treatment of GERD.Methods:A total of 200 first-visit prescriptions from Prof.Zha Ansheng's outpatient clinic for GERD patients(from September 1,2023,to October 1,2024)were collected.A prescription database was established.After standard-ized processing,frequency statistics were performed on the herbs,their properties,flavors,meridian tropisms,and medicinal categories.Bivariate,trivariate and multivariate association analyses as well as complex network analysis were conducted on herbs with a frequency>50.Results:The top 10 most frequently used herbs were:Chenpi,Banxia,Baizhu,Zhiqiao,Pugongying,Zhebeimu,Muxiang,Sharen,Foshou,and Baiji.The predominant herb properties were warm and cold;the main flavors were bitter and pungent;the herbs mainly acted on the spleen and stomach meridians.Frequency analysis of herb categories showed that Qi-regulating herbs,heat-clearing herbs,phlegm-resolving,cough-relieving,and asthma-relieving herbs,dampness-resolving herbs,and deficiency-tonifying herbs ranked in the top five.Association rule analysis indicated that Muxiang-Sharen,Chenpi-Sharen,and Chenpi-Muxiang were commonly used herb pairs,with a high likelihood of the combination of Muxiang,Sharen,and Banxia.Chenpi,Sharen,Muxiang,and Banxia showed strong associations.Complex network analysis yielded the core prescription:Chenpi,Banxia,Zhiqiao,Baizhu,Muxiang and Sharen.Conclusion:Prof.Zha Ansheng's approach to treat-ing GERD focuses on regulating Qi,strengthening the spleen,harmonizing the stomach,and resolving dampness,supple-mented by clearing heat,resolving phlegm,and tonifying deficiency.This promotes Qi flow,strengthens the spleen,clears heat,resolves dampness,and eliminates phlegm,thereby restoring the normal ascending and descending functions of the spleen and stomach Qi activity.The core formulas are Erchen Decoction,Zhizhu Pill,and Xiangsha Liujunzi Decoction.关键词
胃食管反流病/数据挖掘技术/名医经验/查安生/用药规律Key words
GERD/data mining technology/famous physician's experience/Zha Ansheng/medication rules分类
医药卫生引用本文复制引用
曹静,任文文,周佳保,查安生..基于数据挖掘技术探讨查安生教授治疗胃食管反流病用药规律[J].山西中医药大学学报,2026,27(6):610-615,6.基金项目
国家中医药管理局第七批师承项目(国中医药人教函[2022]76号) （国中医药人教函[2022]76号）
2024年安徽省卫健委项目(AHWJ2024BAf30047) （AHWJ2024BAf30047）
安徽省查安生名中医工作室项目([2020]10号) （[2020]10号）
安徽省临床重点专科项目([2020]243号) （[2020]243号）
安徽中医药大学2024年校级教学研究项目(2024xjjy_yb050) （2024xjjy_yb050）
