山西中医药大学学报2026，Vol.27Issue(6)：678-682,5.DOI:10.19763/j.cnki.2096-7403.2026.06.23
基于温阳散寒活血法探讨桂枝茯苓丸加减治疗癌性疼痛
Exploration of the treatment of cancer pain with modified Guizhi Fuling Pills based on the method of warming Yang,dispersing cold,and activating blood circulation
摘要
Abstract
Pain caused by cancer significantly affects patients'survival time and quality of life.Therefore,effectively al-leviating pain and improving survival rates and quality of life have become critical issues that cannot be ignored in clinical treatment.Modern medicine follows the"three-step analgesic ladder'principle,which has certain efficacy but is often ac-companied by significant adverse reactions and drug resistance.According to traditional Chinese medicine theory,the patho-genesis of cancer pain primarily involves internal insufficiency of Yang Qi and external cold congelation and blood stasis.Guizhi Fuling Pills,a classic formula in Chinese medicine for warming and unblocking meridians,dispelling cold,and acti-vating blood circulation to resolve stasis,originates from the Synopsis of the Golden Chamber.Originally used to treat abdomi-nal masses and metrostaxis in women,this formula has been widely applied in the treatment of gynecological diseases.Given the characteristics of cancer pain,which include Yang deficiency,cold congelation,and blood stasis,this paper systemati-cally explores the rationale for the application of Guizhi Fuling Pills and its modified formulas in the treatment of cancer pain,starting from classical traditional Chinese medicine theories and integrating modern pharmacological research.It em-phasizes the synergistic effects of warming Yang,dispersing cold,and activating blood circulation to resolve stasis,aiming to expand the application of classical formulas in supportive care for cancer pain and provide new insights and clinical refer-ences for traditional Chinese medicine participation in cancer pain management.关键词
癌性疼痛/温阳散寒活血/桂枝茯苓丸/中医Key words
cancer pain/warming Yang,dispersing cold,and activating blood circulation/Guizhi Fuling Pills/tradi-tional Chinese medicine分类
医药卫生引用本文复制引用
李长林,郑广达,尚璐,任娟霞,王凌云,李东滔,刘海啸,鲍艳举..基于温阳散寒活血法探讨桂枝茯苓丸加减治疗癌性疼痛[J].山西中医药大学学报,2026,27(6):678-682,5.基金项目
中央高水平中医医院临床研究和成果转化能力提升项目——医疗机构制剂研发与新药转化专项(HLCMHPP2023078) （HLCMHPP2023078）
