上海针灸杂志2026，Vol.45Issue(6)：636-641,6.DOI:10.13460/j.issn.1005-0957.2026.06.0636
针刺联合低强度抗阻运动治疗老年肌少症的疗效观察
Clinical efficacy of acupuncture combined with low-intensity resistance exercise for sarcopenia in older adults
摘要
Abstract
Objective To observe the clinical efficacy and safety of acupuncture combined with low-intensity resistance exercise in the treatment of sarcopenia in older adults.Method A total of 130 older adults with sarcopenia were randomly assigned to a control group and an observation group using a random number table method,with 65 cases in each group.Both groups received the same nutritional support.The control group received low-intensity resistance exercise,whereas the observation group received acupuncture combined with low-intensity resistance exercise.Clinical efficacy and adverse events were compared between the two groups.Changes in traditional Chinese medicine(TCM)symptoms scores,physical function indicators[short physical performance battery(SPPB)score and handgrip strength],and serum inflammatory factors[C-reactive protein(CRP),interleukin-6(IL-6),and interleukin-8(IL-8)]were assessed before and after treatment.Result The total effective rate was 87.7%in the observation group,significantly higher than 66.2%in the control group(P＜0.05).After treatment,scores for all individual TCM symptom items decreased significantly in both groups compared with baseline(P＜0.05),and were lower in the observation group than in the control group(P＜0.05).SPPB scores and handgrip strength increased significantly in both groups after treatment(P＜0.05),with greater improvements observed in the observation group(P＜0.05).Serum levels of CRP,IL-6,and IL-8 decreased significantly in both groups after treatment(P＜0.05),and were lower in the observation group than in the control group(P＜0.05).There was no significant difference in the overall incidence of adverse events between the two groups(P＞0.05).Conclusion On the basis of nutritional support,acupuncture combined with low-intensity resistance exercise can significantly improve clinical symptoms and physical function in older adults with sarcopenia,thereby enhancing clinical efficacy.These benefits may be associated with attenuation of systemic inflammatory responses.关键词
针刺疗法/抗阻运动/肌少症/炎症因子/老年人Key words
Acupuncture therapy/Resistance exercise/Sarcopenia/Inflammatory factors/Elderly adults分类
医药卫生引用本文复制引用
何孝晴,李宁,徐素芝..针刺联合低强度抗阻运动治疗老年肌少症的疗效观察[J].上海针灸杂志,2026,45(6):636-641,6.基金项目
河北省中医药管理局科研计划项目(2022413) （2022413）
