世界科学技术-中医药现代化2026,Vol.28Issue(6):1728-1748,21.DOI:10.11842/wst.20250826001
颈舒颗粒的化学成分与药理作用研究进展及其质量标志物(Q-marker)预测
Research Progress of Chemical Components,Pharmacological Effects and Quality Marker Prediction of the Jingshu Keli
摘要
Abstract
Jingshu Keli is a traditional Chinese medicine composed of seven kinds of medicinal plants,Panax notoginseng,Angelica sinensis,Ligusticum chuanxiong,Carthamus tinctorius,Gastrodia elata,Cinnamomum cassia,and artificial bovis calculus.It is widely used in clinical practice for the treatment of cervical spondylotic radiculopathy and other shoulder and neck diseases.Modern research shows that Jingshu Keli exhibit anti-inflammatory,analgesic,neuroprotective,and microcirculation-improving effects.This article reviewed the main progress on studies of chemical components,pharmacological effects.And based on the"Five Principles"of quality markers for traditional Chinese medicine,the quality markers of Jingshu Keli were predicted.It was suggested that notoginsenoside R1,ginsenoside Rg1,ginsenoside Rb1,ferulic acid,ligustilide,coniferyl ferulate,senkyunolide A,senkyunolide I,hydroxysafflor yellow A,cinnamaldehyde,cinnamic acid,gastrodin and cholic acid could be used as the quality markers of Jingshu Keli.关键词
颈舒颗粒/化学成分/药理作用/质量标志物/三七Key words
Jingshu Keli/Chemical components/Pharmacological effects/Quality marker/Panax notoginseng分类
医药卫生引用本文复制引用
左言东,杨洁,高武,王珏,沈硕,王玉明,谭宸琛,李遇伯..颈舒颗粒的化学成分与药理作用研究进展及其质量标志物(Q-marker)预测[J].世界科学技术-中医药现代化,2026,28(6):1728-1748,21.基金项目
国家自然科学基金委员会青年科学基金项目(81903938):基于功能代谢组学探讨薏苡附子散治疗类风湿性关节炎和慢性心力衰竭"异病同治"的生物学机制,负责人:王玉明 (81903938)
国家中医药管理局青年岐黄学者支持项目,负责人:李遇伯. ()