世界中医药2026，Vol.21Issue(6)：1077-1083,7.DOI:10.3969/j.issn.1673-7202.2026.06.018
传统运动联合热量限制对超重/肥胖者体质量及肠道菌群的影响
Traditional Exercise Combined with Caloric Restriction Intervention Effects on Body Weight and Gut Microbiota in Overweight/Obese Individuals
摘要
Abstract
Objective:To observe the effects of traditional exercise combined with caloric restriction on body weight and gut micro-biota in overweight/obese individuals.Methods:From June to July 2022,20 participants were recruited through outpatient clinics and community announcements of the Affiliated Hospital of Traditional Chinese Medicine,Ningxia Medical University.Among them,10 overweight/obese participants who met the inclusion criteria were assigned to the observation group,and 10 normal-weight participants were assigned to the control group.Body weight was measured before intervention and two months after intervention.Fe-cal samples were collected for DNA extraction and high-throughput sequencing analysis.Results:A total of eight participants in each group completed the intervention and sample collection.Body mass index(BMI)decreased more significantly in the observation group.Two months after intervention,gut microbiota diversity and richness in the observation group approached those of the control group,while these indices in the control group further improved.At the phylum level,after two months of intervention,the relative a-bundances of Proteobacteria and Fusobacteria in the observation group were significantly decreased(P＜0.05)and approached those of the control group.The Firmicutes/Bacteroidetes ratio in the observation group decreased by 0.195,approaching the level of the con-trol group,while in the control group it decreased by 0.087,with a smaller reduction than that in the observation group.At the genus level,after two months of intervention,the abundances of Escherichia and Anaerotruncus in the observation group were significantly reduced(P＜0.05)and approached those of the control group.Conclusion:Two months after combined intervention,weight rebound in overweight/obese participants was smaller than that in normal-weight participants.However,gut microbiota structure and function were improved in both groups,with more pronounced improvements observed in the overweight/obese group.关键词
传统运动/热量限制/辟谷/超重/肥胖/肠道菌群/体质量Key words
Traditional exercise/Caloric restriction/Bigu/Overweight/obesity/Gut microbiota/Body weight分类
医药卫生引用本文复制引用
燕晓雯,陈建梅,王沐寒,张盛军,马英锋,李保有,郭建红..传统运动联合热量限制对超重/肥胖者体质量及肠道菌群的影响[J].世界中医药,2026,21(6):1077-1083,7.基金项目
国家自然科学基金项目(82360967) （82360967）
宁夏回族自治区自然科学基金重点项目(2025AAC020076). （2025AAC020076）
