护理研究2026，Vol.40Issue(14)：2385-2392,8.DOI:10.12102/j.issn.1009-6493.2026.14.001
家庭护士食疗理论在超重和肥胖围绝经期综合征病人中的实证研究
Empirical study of the family nurse dietary therapy theory in overweight and obese patients with perimenopausal syndrome
摘要
Abstract
Objective:To observe the effectiveness of a family nurse dietary therapy regimen,developed based on the family nurse dietary therapy theory,in improving the severity of menopausal symptoms,metabolic indicators,and oxidative stress levels in overweight and obese patients with perimenopausal syndrome.Methods:A total of 70 overweight and obese patients with perimenopausal syndrome were selected as study subjects from the gynecology outpatient clinic of a tertiary grade A hospital and a resident community in Shanxi province from May 25,2025 to August 29,2025.Patients were randomly divided into control group and intervention group,35 cases each.The control group patients received a conventional dietary program,while the intervention group cases received the family nurse dietary therapy regimen in addition to routine care.Anthropometric indicators,blood biochemical indicators,inflammatory indicators,and oxidative stress indicators were evaluated before the intervention and 6 weeks after the intervention.Results:During the intervention period,8 cases dropped out,31 patients in each group completed the trial.After 6 weeks of intervention,the intervention group demonstrated significantly lower levels than those before the intervention in terms of body weight,body mass index(BMI),waist circumference,abdominal circumference,hip circumference,body fat mass,visceral fat area,fasting plasma glucose(FPG),fasting insulin(FINS),homeostatic model assessment for insulin resistance(HOMA-IR),total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),homocysteine(Hcy),alanine aminotransferase(ALT),aspartate aminotransferase(AST),blood urea nitrogen(BUN),serum creatinine(Scr),serum uric acid(UA),tumor necrosis factor-alpha(TNF-α),high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),and malondialdehyde(MDA).Furthermore,the BMI,abdominal circumference,hip circumference,body fat mass,FPG,HOMA-IR,TG,LDL-C,Hcy,TNF-α,hs-CRP,IL-6,and MDA were significantly lower in the intervention group than that in the control group at the same time.Superoxide dismutase(SOD)levels were higher in the intervention group than that before the intervention.The SOD was significantly higher in the intervention group that in the control group at the same time(P<0.05).Conclusions:The family nurse dietary therapy regimen,rich in non-nutrients,alleviated menopausal symptoms and effectively improved body composition,glucose and lipid metabolism,and inflammatory and oxidative stress levels in overweight and obese patients with perimenopausal syndrome.关键词
家庭护士食疗理论/超重/肥胖/围绝经期综合征/非营养素/饮食干预Key words
family nurse dietary therapy theory/overweight/obesity/perimenopausal syndrome/non-nutrients/dietary intervention引用本文复制引用
凌璇,张欢,韩世范,闫蕊,马辰婧,刘洽,吕嘉玲,李馨煜,赵奕雯,张珺..家庭护士食疗理论在超重和肥胖围绝经期综合征病人中的实证研究[J].护理研究,2026,40(14):2385-2392,8.基金项目
2023-2024年度山西省大健康产业高质量发展科研专项项目,编号:DJKZXKT2023002 （）
山西省食疗和农产品处方产业技术创新战略联盟项目 （）
