时珍国医国药2026，Vol.37Issue(13)：2578-2585,8.DOI:10.70976/j.1008-0805.SZGYGY-2026-1325
人参皂苷纳米递送系统抗骨关节炎的应用进展
Recent advances in ginsenoside nanodelivery systems for osteoarthritis treatment
摘要
Abstract
Through systematic retrieval of domestic and international literature,combined with practical application of nanopharmaceu-tical technology and based on pharmacodynamic evaluation,this review systematically summarizes the synergistic mechanisms and safety profiles of ginsenoside nanodelivery systems in osteoarthritis(OA)treatment.Nanodelivery systems significantly improve ginsen-oside bioavailability by enhancing targeted delivery,prolonging joint retention,and increasing cartilage permeability.Future directions include AI-optimized carrier design and establishment of safety evaluation protocols specific to traditional Chinese medicine nan prepara-tions,facilitating clinical translation for improved OA management.关键词
骨关节炎/人参皂苷/纳米递送系统/脂质体/纳米粒Key words
Osteoarthritis/Ginsenoside/Nanodelivery systems/Liposomes/Nanoparticles分类
医药卫生引用本文复制引用
郭天赐,王平,王继达,刘爱峰..人参皂苷纳米递送系统抗骨关节炎的应用进展[J].时珍国医国药,2026,37(13):2578-2585,8.基金项目
国家自然科学基金(82474538,81873316) （82474538,81873316）
天津市津门医学英才项目(TJSJMYXYC-D2-028) （TJSJMYXYC-D2-028）
