武警医学2026，Vol.37Issue(6)：491-496,505,7.DOI:10.3969/j.issn.1004-3594.2026.06.006
类固醇激素与自体骨髓注射结合弹性髓内针治疗儿童长骨单纯性骨囊肿的临床对照研究
Comparative Clinical Study of Corticosteroid versus Autologous Bone Marrow Injection Combined with Elastic Stable Intramedullary Nailing for Pediatric Long-Bone Unicameral Bone Cyst
摘要
Abstract
Objective To compare the efficacy and safety of elastic stable intramedullary nailing(ESIN)combined with corti-costeroid versus combined with autologous bone marrow(ABM)injection in the treatment of unicameral bone cyst(UBC)in the long bones of children.Methods A retrospective analysis was performed on 45 children with UBC admitted to the First and the Seventh Medical Centers of the PLA General Hospital from January 2015 to December 2023.The patients were divided into group A(n=21,ESIN plus corticosteroid)and group B(n=24,ESIN plus ABM injection).Postoperative imaging follow-up was performed regularly,and cyst healing was evaluated according to the Capanna criteria.Results All the 45 patients completed follow-up,with a mean follow-up duration of 40.4 months.The overall effective rate was 90.5%(19/21)in group A and 91.7%(22/24)in group B,with no sta-tistically significant difference between the two groups(P=0.89).Among the 45 cases,28(62.2%)achieved complete healing,13(28.9%)had partial healing,2(4.4%)developed recurrence,and 2(4.4%)showed no response to treatment.Conclusions Both ESIN combined with corticosteroid and ESIN combined with ABM injection are safe and effective minimally inva-sive methods for the treatment of UBC.关键词
单纯性骨囊肿/儿童/弹性髓内针/类固醇激素/自体骨髓血Key words
unicameral bone cyst/children/elastic intramedullary nailing/corticosteroid/autologous bone marrow分类
医药卫生引用本文复制引用
杜英杰,姚佳岐,刘丽,邓湘玲,李文超..类固醇激素与自体骨髓注射结合弹性髓内针治疗儿童长骨单纯性骨囊肿的临床对照研究[J].武警医学,2026,37(6):491-496,505,7.基金项目
军队某课题资助,北京市自然科学基金(7192196) （7192196）
