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基于光学多点追踪的肝肿瘤热消融呼吸运动建模系统设计

程艳捷 吴薇薇 吴水才

医疗卫生装备2026,Vol.47Issue(6):29-36,8.
医疗卫生装备2026,Vol.47Issue(6):29-36,8.DOI:10.19745/j.1003-8868.2026087

基于光学多点追踪的肝肿瘤热消融呼吸运动建模系统设计

Design of respiratory motion modeling system for liver tumor thermal ablation based on optical multi-point tracking

程艳捷 1吴薇薇 2吴水才1

作者信息

  • 1. 北京工业大学化学与生命科学学院,北京 100124
  • 2. 首都医科大学生物医学工程学院,北京 100069
  • 折叠

摘要

Abstract

Objective To design an optical multi-point tracking-based respiratory motion modeling system for liver tumor thermal ablation,so as to address the challenge of accurately marking the center of a tumor during thermal ablation of liver tumors where respiratory motion causes the tumor's position to shift.Methods The optical multi-point tracking-based respiratory motion modeling system had its hardware composed of an optical positioning system and a respiratory device,which worked in conjunction with a host computer platform to handle system control and data processing;the software of the system was programmed with Python 3.8 language,which used the multiple linear regression algorithm from scikit-learn for model training and prediction,and employed Matplotlib to visualize the comparison between predicted and actual values.The system's performance was validated through standard experiments,noise perturbation experiments and real human data.Results Under standard experimental data,the mean absolute errors(MAEs)of the system for motion prediction in standard breathing,fast breathing and deep breathing modes were all lower than 0.03 mm,and the coefficients of determination R2 were all higher than 0.87.R2 stayed above 0.82 under the noise interference with an amplitude not exceeding 0.05 mm.In real human data experiments,the root mean square error of respiratory motion prediction was within 0.4 mm,R2 was higher than 0.94 and MAE was lower than 0.3 mm.Conclusion The system accurately predicts the displacement of the tumor center at real time,which features high anti-interference capability and clinical applicability and provides reliable technical support for real-time respiratory motion compensation and intraoperative displacement prediction in liver tumor thermal ablation.[Chinese Medical Equipment Journal,2026,47(6):29-36]

关键词

光学多点追踪/肝肿瘤热消融/呼吸运动/多元线性回归/呼吸运动补偿

Key words

optical multi-point tracking/liver tumor thermal ablation/respiratory motion/multiple linear regression/respiratory motion compensation

分类

医药卫生

引用本文复制引用

程艳捷,吴薇薇,吴水才..基于光学多点追踪的肝肿瘤热消融呼吸运动建模系统设计[J].医疗卫生装备,2026,47(6):29-36,8.

基金项目

北京市教育委员会科研计划项目(KM202310025019) (KM202310025019)

医疗卫生装备

1003-8868

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