云南化工2026，Vol.53Issue(6)：24-28,5.DOI:10.3969/j.issn.1004-275X.2026.06.06
剑叶玉簪总黄酮提取及活性研究
Extraction and Activity Study of Total Flavonoids from Hosta ensata F.Maekawa
摘要
Abstract
Using dried and pulverized Hosta ensata flowers as the raw material,the extraction process for total flavonoids was optimized through single-factor experiments combined with orthogonal tests.Results demonstrated that the optimal extraction conditions were a solid-liquid ratio of1∶40,60℃,20 min,and 90%ethanol,achieving a yield of(6.114±0.056)mg/g.Further antioxidant assays revealed that the total fla-vonoids from Hosta ensata exhibited significantly stronger scavenging activity against ABTS+·compared to VC(p<0.05).At lower concen-trations,their DPPH·and·OH scavenging capacities also surpassed those of VC(p<0.05).However,their ferric ion-reducing power was weaker than VC when the concentration exceeded0.1 mg·mL-1(p<0.05)but showed no significant difference at concentrations≤0.05 mg·mL-1(p>0.05).The CCK-8 assay demonstrated that the total flavonoids significantly inhibited the proliferation of gastric cancer BGC823 cells,with an IC50 value of 23.84 μg·mL-1.In conclusion,the total flavonoids from Hosta ensata exhibit remarkable antioxidant and antitumor activities,highlighting their potential for further development in pharmacological or nutraceutical applications.关键词
剑叶玉簪/提取工艺/总黄酮/抗氧化/抗肿瘤Key words
Hosta ensata/Extraction Process/Total Flavonoids/Antioxidant/Antitumor分类
医药卫生引用本文复制引用
叶静,孙士红,薛柏吉..剑叶玉簪总黄酮提取及活性研究[J].云南化工,2026,53(6):24-28,5.基金项目
吉林省教育厅科学技术研究项目(JJKH20241100KJ,JJKH20251852KJ) （JJKH20241100KJ,JJKH20251852KJ）
吉林省科技发展计划(YDZJ202401098ZYTS). （YDZJ202401098ZYTS）
