医药导报2026，Vol.45Issue(6)：1097-1101,5.DOI:10.3870/j.issn.1004-0781.2026.06.022
心脏机械瓣膜患者行脑血管介入术围手术期抗栓治疗的药学服务
Pharmaceutical Services for Perioperative Antithrombotic Therapy in Patients with Mechanical Heart Valves Undergoing Cerebrovascular Intervention
张晚霞 1周呈瑞 2赵燕2
作者信息
- 1. 中部战区总医院临床药学科,武汉 430070||湖北省第三人民医院药学部,武汉 430033
- 2. 中部战区总医院临床药学科,武汉 430070
- 折叠
摘要
Abstract
Objective To explore the perioperative antithrombotic therapy strategies and the connotation of pharmaceu-tical care for patients undergoing cerebrovascular stent implantation after mechanical heart valve replacement.Methods Clini-cal pharmacists participated in the perioperative antithrombotic treatment process of a patient who underwent cerebrovascular stent implantation after cardiac valve replacement,assisted physicians in formulating and optimizing the perioperative antithrombotic therapy plan,and provided the patient with full-course pharmaceutical care.Results The patient did not experience thrombo-embolic or bleeding events during hospitalization and was discharged after recovery.The discharge antithrombotic regimen was as-pirin combined with warfarin for six months,followed by long-term anticoagulation with warfarin alone.The patient has remained stable after discharge,and the international normalized ratio(INR)has reached the target range.Conclusions The key to the perioperative antithrombotic therapy strategy for patients undergoing cerebrovascular interventional surgery after heart mechani-cal valve replacement lies in the assessment of thromboembolic risk and bleeding risk.Clinical pharmacists should establish a full-course pharmaceutical care model encompassing risk prediction,regimen optimization,pharmaceutical monitoring,patient educa-tion and follow-up,so as to give full play to their role in ensuring safe medication use.关键词
心脏瓣膜置换术后/脑血管支架置入术/抗栓治疗/药学服务Key words
Post-cardiac valve replacement/Cerebrovascular stent implantation/Antithrombotic therapy/Pharmaceuti-cal care分类
医药卫生引用本文复制引用
张晚霞,周呈瑞,赵燕..心脏机械瓣膜患者行脑血管介入术围手术期抗栓治疗的药学服务[J].医药导报,2026,45(6):1097-1101,5.
