应用化学2026，Vol.43Issue(6)：897-905,9.DOI:10.19894/j.issn.1000-0518.250486
氧空位诱导的TiO2/BiOI基光电化学分子印迹传感器的构建及多巴胺检测
Oxygen Vacancies-Induced TiO2/BiOI-Based Photoelectrochemical Molecular Imprinting Sensor and Dopamine Detection
摘要
Abstract
Dopamine(DA),as an important neurotransmitter in the central nervous system,its precise detection is of great significance for the early diagnosis of diseases,treatment monitoring,and neurophysiological research.This study successfully constructed a TiO2/BiOI-based photoelectrochemical molecularly imprinted biosensor through an oxygen vacancies(OVs)regulation strategy.The introduction of OVs not only enhances the light absorption performance of TiO2/BiOI but also promotes the formation of P-N heterojunctions,facilitating the rapid separation of photo-generated carriers and significantly improving the sensor's sensitivity.Additionally,the introduction of OVs facilitates the modification of organic molecules on the electrode surface,thereby improving the sensor's selectivity and stability in dopamine detection.The results show that the sensor exhibits good linearity in dopamine detection over a range of 0.5～2.5 μmol/L,with a detection limit of 150.0 nmol/L.It also demonstrates strong non-specificity toward interfering biomolecules such as urea and glucose.This study provides a new approach for constructing high-sensitivity and high-selectivity molecularly imprinted photoelectrochemical biosensors by investigating the regulatory mechanism of oxygen vacancies,offering broad application prospects in biomolecular detection.关键词
光电化学传感器/氧空位/TiO2/BiOI异质结/分子印迹技术/多巴胺Key words
Photoelectrochemical sensor/Oxygen vacancy/TiO2/BiOI heterojunction/Molecularly imprinted technology/Dopamine分类
化学化工引用本文复制引用
辛艳梅,张瑞婷,王惠卿,关二不,李帅帅,吴兴雷..氧空位诱导的TiO2/BiOI基光电化学分子印迹传感器的构建及多巴胺检测[J].应用化学,2026,43(6):897-905,9.基金项目
国家自然科学基金(No.22404111)和教育部高等学校科学研究发展中心项目(No.2024MZ011)资助 Supported by the National Natural Science Foundation of China(No.22404111)and the Center for Scientific Research Development of the Ministry of Education(No.2024MZ011) （No.22404111）
