中国防痨杂志2026，Vol.48Issue(7)：965-971,7.DOI:10.19982/j.issn.1000-6621.20260050
1007例糖尿病患者结核分枝杆菌潜伏感染现状及相关因素分析
Analysis of latent tuberculosis infection prevalence and its related factors in 1007 patients with diabetes mellitus
摘要
Abstract
Objective:To understand the prevalence of latent tuberculosis infection(LTBI)and its related factors in patients with diabetes mellitus,and to provide evidences for pulmonary tuberculosis prevention and control in this high-risk group.Methods:A cross-sectional survey was conducted for 1007 diabetes mellitus patients underwent LTBI screening in Anji County,Zhejiang Province from April 2024 to December 2024.The data of LTBI screening and diabetes mellitus patients were sourced from the local regional cloud medical information system.With the interferon gamma release assay(IGRA)for detection,the prevalence of LTBI in diabetes mellitus patients was described and related factors were analyzed with the multivariate logistic regression model.Results:Among 1007 diabetes mellitus patients,149 were positive for IGRA,and no active pulmonary tuberculosis was found.The latent tuberculosis infection rate was 14.8％.The results of multivariate analysis showed that age ≥60 years(OR=1.788,95％CI:1.159-2.760),daily smoking ≤20 cigarettes(OR=1.694,95％CI:1.004-2.857),＞20 cigarettes(OR=2.650,95％CI:1.079-6.506),and average psychological adjustment status(OR=1.674,95％CI:1.176-2.384)were related factors for LTBI in diabetes mellitus patients.Conclusion:The LTBI rate in diabetes mellitus patients is at a relatively high level,and age,smoking,and psychological status are related factors.It is suggested that active screening of pulmonary tuberculosis should be emphasized in the management of diabetes,and key interventions should be carried out for the elderly,smokers and those with poor mental status.关键词
糖尿病/结核/分枝杆菌感染/因素分析,统计学Key words
Diabetes/Tuberculosis/Mycobacterium infection/Factor analysis,statistical分类
医药卫生引用本文复制引用
游继存,田磊,汪玲燕,杨中荣,沈建勇,陈彬..1007例糖尿病患者结核分枝杆菌潜伏感染现状及相关因素分析[J].中国防痨杂志,2026,48(7):965-971,7.基金项目
国家重点研发计划课题(2024YFC2311202) （2024YFC2311202）
浙江省疾病预防控制科技计划项目(2025JK178 （）
2026JKY085) （）
浙江省疾病预防控制创新团队(2026JKC-05) National Key Research and Development Program Project(2024YFC2311202) （2026JKC-05）
Zhejiang Province Disease Prevention and Control Technology Plan Project(2025JK178 （）
2026JKY085) （）
Zhejiang Province Disease Prevention and Control Innovation Team(2026JKC-05) （2026JKC-05）
