摘要
Abstract
Objective:To study the effect of the same-position MRI with CT simulation localization images fusion in pre-cise radiotherapy of brain glioma patients.Methods:In this prospective study,86 patients with brain glioma who received treatment from June 2021 to September 2024 were selected as the research objects.According to the principle of randomiza-tion,the above patients were randomly divided into the study group and the control group.The patients in the study group received radiation therapy with the same-position MRI with CT simulation localization images fusion.The control group was treated with radiation therapy combined with conventional MRI imaging and simulated CT localization images.The accuracy of the images,the volume of the fused images,and the dosimetry,clinical target,planned target,and dosimetry differences were compared between the two groups.Result:In the study group,the Dice similarity cofficient(DSC)values for the whole brain,brainstem,left eye,right eye,left lens,right lens,left optic nerve,right optic nerve,optic chiasm,and pituitary gland were significantly higher than in the control group.The Hausdorff distance(HD)values for the right lens,left optic nerve,right optic nerve,optic chiasm,and pituitary gland were significantly lower than in the control group.The sketched volume and sketched dosimetry indexes of the whole brain,brainstem,left eyeball,right eyeball,left lens,right lens,left optic nerve,right optic nerve,chiasma optic,pituitary gland were not statistically significant between the study group and the control group(P＞0.05).The clinical target volume and planned target volume were significantly higher in the study group(P＜0.05),but there were no statistically significant differences in the clinical target dose and planned target dose between the two groups(P＞0.05).Conclu-sion:The same-position MRI with CT simulation localization images fusion helps to improve the accuracy of the image in the precision radiotherapy of brain glioma patients,but there is little difference in dosimetry and volume between the planned tar-get and the clinical target.关键词
脑肿瘤/神经胶质瘤/磁共振成像/体层摄影术,螺旋计算机Key words
Brain Neoplasms/Glioma/Magnetic Resonance Imaging/Tomography,Spiral Computed分类
医药卫生
