中国实用妇科与产科杂志2026，Vol.42Issue(6)：596-600,5.DOI:10.19538/j.fk2026060106
孕产妇脓毒症的集束化管理
Bundle management of maternal sepsis
摘要
Abstract
Maternal sepsis is a severe infectious condition occurring during pregnancy and the puerperium that poses a significant threat to both maternal and fetal health.Glob-ally,it remains one of the leading causes of maternal mor-tality.The unique physiological changes associated with pregnancy may obscure the early manifestations of sepsis,thereby contributing to delayed clinical diagnosis and un-timely intervention.Bundle management,which integrates a series of evidence-based standardized interventions,pro-vides a systematic framework for the standardized diagnosis and treatment of obstetric sepsis.Upon early identification of sepsis,the bundle management of obstetric sepsis should be initiated promptly.This includes the measures concerning lactate measurement,microbiological cultures,administration of broad-spectrum antibiotics,fluid resusci-tation,and the use of vasopressors,with careful consider-ation of obstetric-specific adaptations.Particular emphasis should be placed on the timeliness of antibiotic therapy and adherence to the principle of de-escalation.Sepsis itself is not an indication for termination of pregnancy;in most cas-es,pregnancy can be safely continued once the underlying cause of infection is identified and appropriately managed.关键词
产科脓毒症/集束化管理/产科适配策略/抗感染/多学科协作Key words
obstetric sepsis/bundle management/obstet-ric adaptation/anti-infection/multidisciplinary collabora-tion分类
医药卫生引用本文复制引用
姬晓宇,陈鹏正,王谢桐..孕产妇脓毒症的集束化管理[J].中国实用妇科与产科杂志,2026,42(6):596-600,5.基金项目
国家重点研发计划(2024YFC2707500) Nation Key R&D Program of China(2024YFC2707500) （2024YFC2707500）
