中国畜牧兽医2026，Vol.53Issue(7)：3491-3500,10.DOI:10.16431/j.cnki.1671-7236.2026.07.009
围产期奶牛酮病发病机制及防控措施研究进展
Research Progress on the Pathogenesis and Preventive Measures of Ketosis in Perinatal Dairy Cows
摘要
Abstract
With the continuous advancement of modern dairy cow breeding technology and ongoing improvements in feeding management,the milk yield of dairy cows has increased gradually.However,high milk yield has led to the increasingly prominent problem of negative energy balance in perinatal dairy cows.Under conditions of negative energy balance,blood glucose concentration decreases,and the mobilization of body fat increases,resulting in a significant rise in ketone body levels,such as β-hydroxybutyric acid,thereby inducing subclinical or clinical ketosis.Ketosis reduces production performance,immune function,and reproduction,enhances susceptibility to secondary diseases such as mastitis and endometritis,and increases the mortality rate of dairy cows,it seriously restricts the high-quality development of dairy farming.Exploring the pathogenesis of ketosis,identifying its pathogenic factors,and establishing a comprehensive prevention and control system are essential for reducing the incidence of ketosis in perinatal dairy cows.This paper elaborates on the pathogenesis of ketosis,and summarizes research progress on pathogenic factors and preventive measures,providing theoretical references for improving dairy cow production performance and preventing ketosis.关键词
围产期奶牛/酮病/发病机制/防控措施Key words
perinatal dairy cows/ketosis/pathogenesis/preventive measures分类
农业科技引用本文复制引用
王美美,白露,刘畅,李恬娇,马峰涛,徐宏建,高艳霞,李建国..围产期奶牛酮病发病机制及防控措施研究进展[J].中国畜牧兽医,2026,53(7):3491-3500,10.基金项目
河北省教育厅科学研究项目(QN2025223) （QN2025223）
财政部和农业农村部-国家现代农业产业技术体系(CARS-36-20) （CARS-36-20）
河北省现代农业产业技术体系奶牛创新团队项目(2023180207) （2023180207）
河北省高端人才项目(6012018) （6012018）
