中国医学装备2026，Vol.23Issue(6)：140-144,5.DOI:10.3969/j.issn.1672-8270.2026.06.026
聚焦超声在变应性鼻炎治疗中的应用与研究进展
Application progress of focused ultrasound in the treatment of allergic rhinitis
摘要
Abstract
Allergic rhinitis(AR)is an IgE-mediated chronic noninfectious inflammatory disease of nasal mucosa,with rising global prevalence.Standardized four-in-one comprehensive protocols for prevention and treatment can effectively control symptoms of most patients with mild AR.However,refractory AR is commonly associated with poor medication adherence,and the effect of conservative treatment for that is limited.Persistent recurrent symptoms can markedly impair patients'quality of life and impose an economic burden on public health Focused ultrasound(FUS)can produce targeted submucosal coagulative ablation via thermal,mechanical and cavitation effects,which can feature advantages include minimal invasiveness,repeatable administration,and preservation of physiological structure of epithelial cilia in nasal cavity.FUS has gradually been applied in surgical intervention for AR.This review systematically sorted out the pathophysiological mechanisms that FUS treats AR,application effects of that in differently clinical scenario,perioperative adverse events and safety data.In addition,this review horizontally compared the clinical advantages and disadvantages among FUS and conventional turbinate surgery with coblation and radiofrequency,and hormonal medicines,and summarized the existing technical drawbacks at present.Finally,it looked ahead to future directions of development through combined with research and development of apparatuses,and the research progress of individual parameters.This review can provide evidence-based references for the rational clinical selection of FUS regimens to treat refractory AR.关键词
聚焦超声(FUS)/变应性鼻炎(AR)/鼻甲肥大/微创和(或)无创手术/难治性鼻炎Key words
Focused ultrasound(FUS)/Allergic rhinitis(AR)/Turbinate hypertrophy/Minimal noninvasive surgery/Refractory rhinitis分类
医药卫生引用本文复制引用
郭蓓,高培,王兴龙,刘仁,陈伟..聚焦超声在变应性鼻炎治疗中的应用与研究进展[J].中国医学装备,2026,23(6):140-144,5.基金项目
重庆市科学技术局超声医学国家重点实验室面上项目(2023KFKT005) （2023KFKT005）
重庆市科学技术局超声医学国家重点实验室重点项目(2023KFKT001)State Key Laboratory of Ultrasound in Medicine and Engineering,Chongqing Municipal Science and Technology Bureau(2023KFKT005,2023KFKT001) （2023KFKT001）
