中国针灸2026，Vol.46Issue(6)：875-882,8.DOI:10.13703/j.0255-2930.20250216-k0001
电针对老年维持性血液透析患者睡眠质量、认知功能及脑血流动力学的影响
Effects of electroacupuncture on sleep quality,cognitive function and cerebral hemodynamics in elderly maintenance hemodialysis patients
摘要
Abstract
Objective To observe the effects of electroacupuncture(EA)on sleep quality,cognitive function,sleep process and structure,as well as cerebral hemodynamics in elderly patients with maintenance hemodialysis(MHD).Methods Sixty elderly MHD patients were randomized into an EA group(30 cases)and a sham acupuncture group(30 cases).EA was applied at Sishencong(EX-HN1)in the EA group,with continuous wave,in frequency of 2 Hz and in current of 1 mA.Sham acupuncture was applied at distal non-meridian and non-acupoint points in the sham acupuncture group,same EA parameters were given,and the electrical stimulation was stopped after 30 seconds.Both groups were intervened for 30 min per session,once daily,5 days per week,for a total of 4 weeks.Before and after treatment,the scores of Pittsburgh sleep quality index(PSQI),insomnia severity index(ISI),Montreal cognitive assessment-basic(MoCA-B),mini-mental state examination(MMSE)were observed,and the incidence of sleep disorders was calculated based on PSQI score;the indexes of sleep process(sleep onset latency[SOL],total sleep time[TST],sleep efficiency[SE])and sleep structure(percentages of stage 1 sleep[N1],stage 2 sleep[N2],stage 3 sleep[N3]and rapid eye movement sleep[REM]in TST)were observed by polysomnography system;and the cerebral hemodynamic indexes(mean blood flow velocity[Vm]of middle artery,regional cerebral blood flow[rCBF]and regional cerebral blood volume[rCBV])were detected by transcranial Doppler ultrasound in the two groups.Results After treatment,the PSQI score,incidence of sleep disorders and ISI score in the EA group were decreased(P＜0.05),while the scores of MoCA-B and MMSE were increased compared with those before treatment(P＜0.05);in the EA group,the PSQI score,incidence of sleep disorders and ISI score were lower,while the scores of MoCA-B and MMSE were higher than those in the sham acupuncture group(P＜0.001).Compared before treatment,SOL was shortened,TST was prolonged,the percentage of N1 in TST was decreased,the percentages of N2,N3 and REM in TST were increased,and SE was improved in the EA group after treatment(P＜0.05);after treatment,all indexes of sleep process and structure in the EA group were superior to those in the sham acupuncture group(P＜0.001,P＜0.01).After treatment,the Vm of middle artery,rCBF and rCBV in the EA group were increased compared with those before treatment(P＜0.05);the Vm of middle artery,rCBF and rCBV in the EA group were higher than those in the sham acupuncture group(P＜0.001).Conclusion EA can regulate sleep process and structure,and improve sleep quality and cognitive function in elderly MHD patients,which may be related to the improvement of cerebral hemodynamics.关键词
终末期肾病/维持性血液透析/电针/四神聪/睡眠质量/睡眠结构/认知功能/脑血流动力学/随机对照试验Key words
end-stage renal disease/maintenance hemodialysis/electroacupuncture/Point EX-HN1(Sishencong)/sleep quality/sleep structure/cognitive function/cerebral hemodynamics/randomized controlled trial(RCT)引用本文复制引用
李景兴,刘卓麟..电针对老年维持性血液透析患者睡眠质量、认知功能及脑血流动力学的影响[J].中国针灸,2026,46(6):875-882,8.基金项目
衡阳市科技计划项目:202323036685 （）
