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HBx-mediated GPT2 suppression promotes liver cancer development by downregulating ADH1A

Hongjuan You Delong Kong Xiucheng Pan Xiaocui Li Suping Qin Kuiyang Zheng Chen Li Renxian Tang Fanyun Kong Xing Wang Ruyu Liu Yuxin Wang Huanyang Zhang Lihong Ma Ensi Bao Yujie Zhong Xiangye Liu

癌症生物学与医学（英文版）2026，Vol.23Issue(6)：888-909,22.

癌症生物学与医学（英文版）2026，Vol.23Issue(6)：888-909,22.DOI:10.20892/j.issn.2095-3941.2025.0236

HBx-mediated GPT2 suppression promotes liver cancer development by downregulating ADH1A

Hongjuan You ¹Delong Kong ¹Xiucheng Pan ²Xiaocui Li ¹Suping Qin ¹Kuiyang Zheng ³Chen Li ¹Renxian Tang ³Fanyun Kong ¹Xing Wang ⁴Ruyu Liu ⁵Yuxin Wang ¹Huanyang Zhang ¹Lihong Ma ¹Ensi Bao ¹Yujie Zhong ¹Xiangye Liu¹

作者信息

1. Jiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China
2. Department of Infectious Diseases,The Affiliated Hospital of Xuzhou Medical University,Xuzhou 221006,China
3. Jiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China||National Demonstration Center for Experimental Basic Medical Sciences Education,Xuzhou Medical University,Xuzhou 221004,China
4. Jiangsu Key Laboratory of Immunity and Metabolism,Department of Pathogenic Biology and Immunology,School of Basic Medical Sciences,Xuzhou Medical University,Xuzhou 221004,China||Department of Clinical Laboratory,Heping Hospital Affiliated to Changzhi Medical College,Changzhi 046000,China
5. Department of Hepatology Division,Beijing Ditan Hospital Affiliated to Capital Medical University Xuzhou Hospital and Xuzhou Seventh People's Hospital,Xuzhou 221004,China
折叠

摘要

关键词

Liver cancer/HBx/GPT2/ADH1A/CBL/LSD1

Key words

Liver cancer/HBx/GPT2/ADH1A/CBL/LSD1

引用本文复制引用

Hongjuan You,Delong Kong,Xiucheng Pan,Xiaocui Li,Suping Qin,Kuiyang Zheng,Chen Li,Renxian Tang,Fanyun Kong,Xing Wang,Ruyu Liu,Yuxin Wang,Huanyang Zhang,Lihong Ma,Ensi Bao,Yujie Zhong,Xiangye Liu..HBx-mediated GPT2 suppression promotes liver cancer development by downregulating ADH1A[J].癌症生物学与医学（英文版）,2026,23(6):888-909,22.

基金项目

This study was supported by the Qing Lan Project of Jiangsu Province,the National Natural Science Foundation of China(Grant No.82372245),and a Starting Grant for Talents of Xuzhou Medical University(Grant No.RC20552309). （Grant No.82372245）

癌症生物学与医学（英文版）

ISSN：2095-3941

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