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Expansion of IL-2-independent tumor-infiltrating lymphocytes through a feeder-free process:a preclinical study for solid tumors

Ying Zhang Wenjia Zhuang Huajun Jin Jianming Xu Sicheng Du Rongrui Liu Chuanhua Zhao Juan Li Sisi Ye Man Zhang Xingming Ma Zhou He

癌症生物学与医学（英文版）2026，Vol.23Issue(6)：910-924,15.

癌症生物学与医学（英文版）2026，Vol.23Issue(6)：910-924,15.DOI:10.20892/j.issn.2095-3941.2025.0441

Expansion of IL-2-independent tumor-infiltrating lymphocytes through a feeder-free process:a preclinical study for solid tumors

Ying Zhang ¹Wenjia Zhuang ²Huajun Jin ²Jianming Xu ³Sicheng Du ¹Rongrui Liu ³Chuanhua Zhao ³Juan Li ³Sisi Ye ³Man Zhang ²Xingming Ma ²Zhou He²

作者信息

1. Medical School of Chinese People's Liberation Army(PLA)General Hospital,Beijing 100853,China
2. Shanghai Juncell Therapeutics,Shanghai 201802,China
3. Senior Department of Oncology,Chinese PLA General Hospital,Beijing 100853,China
折叠

摘要

关键词

Tumor-infiltrating lymphocytes/solid tumors/PD-1 blockade/hydroxychloroquine/MHC class Ⅰ

Key words

Tumor-infiltrating lymphocytes/solid tumors/PD-1 blockade/hydroxychloroquine/MHC class Ⅰ

引用本文复制引用

Ying Zhang,Wenjia Zhuang,Huajun Jin,Jianming Xu,Sicheng Du,Rongrui Liu,Chuanhua Zhao,Juan Li,Sisi Ye,Man Zhang,Xingming Ma,Zhou He..Expansion of IL-2-independent tumor-infiltrating lymphocytes through a feeder-free process:a preclinical study for solid tumors[J].癌症生物学与医学（英文版）,2026,23(6):910-924,15.

基金项目

This study was supported by the Science and Technology Innovation Action Plan of the Science and Technology Commission of Shanghai Municipality(STCSM)(Grant No.22XD1432200). （STCSM）

癌症生物学与医学（英文版）

ISSN：2095-3941

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