针灸推拿医学（英文版）2026，Vol.24Issue(3)：292-299,8.DOI:10.1007/s11726-026-1579-4
隔药饼灸神阙治疗寒凝血瘀型原发性痛经:一项随机对照试验
Herb cake-insulated moxibustion at Shenque(CV8)for primary dysmenorrhea of cold-induced blood stasis pattern:a randomized controlled trial
摘要
Abstract
Objective:To observe the clinical efficacy of herb cake-insulated moxibustion at Shenque(CV8)in treating primary dysmenorrhea(PD)of cold-induced blood stasis pattern,and its influence on serum inflammatory factors. Methods:A total of 60 patients with PD of cold-induced blood stasis pattern were randomly divided into an herb cake-insulated moxibustion group and a medication group by the random number table method,with 30 cases in each group.The medication group was treated with oral ibuprofen sustained-release capsules,initiated 3 d before menstruation and continued until the end of the menstrual period.The herb cake-insulated moxibustion group received herb cake-insulated moxibustion at Shenque(CV8),once daily starting 3 d before menstruation until menstruation ended.One menstrual cycle was defined as one treatment course,and both groups received treatment for 3 courses in total.The scores of visual analog scale(VAS)and traditional Chinese medicine symptoms were observed and recorded before and after treatment.In both groups,changes in the serum levels of interleukin(IL)-6,prostaglandin(PG)F2α,PGE2,and β-endorphin(β-EP)were determined before and after treatment.The clinical efficacy was evaluated. Results:The total effective rate was 93.3%in the herb cake-insulated moxibustion group and 80.0%in the medication group,showing no statistically significant difference between the two groups(P>0.05).After treatment,the VAS and traditional Chinese medicine symptom scores decreased significantly in both groups compared with baseline(P<0.05),and the herb cake-insulated moxibustion group showed lower scores than the medication group(P<0.05).The serum levels of IL-6 and PGF2α were reduced in the herb cake-insulated moxibustion group after treatment(P<0.05)and were lower than those in the medication group(P<0.05).The herb cake-insulated moxibustion group also showed increased levels of PGE2 and β-EP after treatment(P<0.05),which were higher than those in the medication group(P<0.05). Conclusion:Herb cake-insulated moxibustion at Shenque(CV8)can alleviate pain and relieve clinical symptoms in patients with PD of cold-induced blood stasis pattern,and can downregulate serum IL-6 and PGF2α levels while upregulating PGE2 and β-EP contents.关键词
灸法/间接灸/药饼灸疗法/穴,神阙/痛经/寒凝血瘀证/随机对照试验Key words
Moxibustion Therapy/Indirect Moxibustion/Herb Cake-insulated Moxibustion/Point,Shenque(CV8)/Dysmenorrhea/Cold-induced Blood Stasis Pattern/Randomized Controlled Trial分类
医药卫生引用本文复制引用
赵敏,陶欢,窦婷婷,王利军,刘灵儿..隔药饼灸神阙治疗寒凝血瘀型原发性痛经:一项随机对照试验[J].针灸推拿医学（英文版）,2026,24(3):292-299,8.基金项目
This study was supported by Innovative Fund Project for University Teachers in Gansu Province in 2024(2024年甘肃省高校教师创新基金项目,No.2024A-217). （2024年甘肃省高校教师创新基金项目,No.2024A-217）
