中外医学研究2026，Vol.24Issue(13)：130-133,4.DOI:10.14033/j.cnki.cfmr.2026.13.032
回顾性分析六君子汤联合司美格鲁肽对初诊2型糖尿病肥胖患者脂质蓄积指数的影响
Retrospective Analysis of the Effect of Combined Use of Six Gentlemen Decoction and Semaglutide on the Lipid Accumulation Index in Obese Patients with Type 2 Diabetes Mellitus at the First Diagnosis
余亚信 1李晨瑶 1陈婧 1陈秋旻 1颜迁州1
作者信息
- 1. 厦门市杏林医院 福建 厦门 361020
- 折叠
摘要
Abstract
Objective:To investigate the effect of combined use of Liujunzi decoction and semaglutide on glucose,blood lipid levels and lipid accumulation index in obese patients with type 2 diabetes mellitus.Method:The clinical data and treatment of 96 obese patients type 2 diabetes mellitus who were initially diagnosed from March 2023 to June 2025 in the hospital were retrospectively analyzed.According to the of treatment methods,they were divided into observation group and control group.The control group(48 cases)was treated with routine type 2 diabetes lifestyle and dietary management subaneous injection of semaglutide,and the observation group(48 cases)was treated with oral administration of Liujunzi decoction on the basis of the control.The blood glucose and blood lipid control effect and lipid accumulation index were compared between the two groups.Result:After treatment,the improvement effects of blood glucose,blood lipid and insulin resistance index(HOMA-IR)in the observation group were better than those in the control group,and the incidences of LAP and adverse reactions were significantly lower than those in the control group.The above differences were statistically significant(P<0.05),while BMI was slightly lower than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion:The combined use of Liujunzi decoction and semaglutide in treatment of obese patients with type 2 diabetes mellitus can further improve the ability to control blood glucose and blood lipid in patients,and help to reduce fat accumulation in patients which is valuable for application and promotion.关键词
六君子汤/司美格鲁肽/2型糖尿病/肥胖/血糖/脂质蓄积指数Key words
Liujunzi decoction/Semaglutide/Type 2 diabetes/Obesity/Blood glucose/Lipid accumulation index引用本文复制引用
余亚信,李晨瑶,陈婧,陈秋旻,颜迁州..回顾性分析六君子汤联合司美格鲁肽对初诊2型糖尿病肥胖患者脂质蓄积指数的影响[J].中外医学研究,2026,24(13):130-133,4.
