摘要
Abstract
Objective To explore the application effect of active risk intervention combined with early prone ventilation nursing in neonatal respiratory distress syndrome(NRDS).Methods A total of 110 neonates with NRDS admitted to Haizhu District Maternal and Child Health Hospital from January 2024 to November 2025 were selected and randomly divided into two groups using the random number table method,with 55 neonates in each group.The control group received routine nursing care,while the observation group received active risk intervention combined with early prone ventilation nursing in addition to routine care.Arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),and oxygenation index(OI)were compared between the two groups before intervention,and at 24 and 48 hours after intervention.The Score for Neonatal Acute Physiology-Ⅱ(SNAP-Ⅱ)was compared before intervention and at 2 and 7 days after intervention.The duration of oxygen therapy,duration of non-invasive mechanical ventilation,length of hospital stay,and incidence of complications were also recorded.Results The effects of intergroup,time,and interaction on PaO2,OI,and PaCO2 were all statistically significant(P<0.05).At 24 and 48 hours after intervention,the observation group had lower PaCO2 levels and higher PaO2 and OI values than the control group(P<0.05).The effects of intergroup,time,and interaction on SNAP-Ⅱ scores were statistically significant(P<0.05).At 2 and 7 days after intervention,the SNAP-Ⅱ scores in the observation group were lower than those in the control group(P<0.05).The observation group had significantly shorter non-invasive mechanical ventilation time and length of hospital stay compared with the control group(P<0.05).The overall incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion Active risk intervention combined with early prone ventilation can effectively improve oxygenation index and ventilatory function in neonates with NRDS,shorten clinical treatment time,and reduce the risk of complications,demonstrating significant clinical comprehensive benefits.关键词
新生儿呼吸窘迫综合征/主动风险干预/俯卧位通气/血气分析指标/氧合指数Key words
neonatal respiratory distress syndrome/active risk intervention/prone ventilation/blood gas analysis indicators/oxygenation index分类
医药卫生
