中医药学报2026，Vol.54Issue(7)：103-108,6.DOI:10.19664/j.cnki.1002-2392.260149
当归拈痛汤联合塞来昔布治疗风湿热痹型神经根型颈椎病的临床观察
Clinical Observation of Danggui Niantong Decoction Combined with Celecoxib in the Treatment of Cervical Spondylotic Radiculopathy with Wind-Damp-Heat Obstruction Syndrome
摘要
Abstract
Objective:To evaluate the efficacy of celecoxib combined with Danggui Niantong Decoction in the treatment of cervical spondylotic radiculopathy Wind-Damp-Heat Obstruction syndrome).Methods:A total of 98 patients with cervical radiculopathy(Wind-Damp-Heat Obstruction syndrome)admitted to the orthopedics and inpatient department of Huanggang Central Hospital from January 2023 to December 2023 were selected as the study objects,and were divided into 2 groups according to random number table method,with 49 cases each.The control group was treated with celecxib on the basis of cervical traction therapy,and the experimental group was treated with Danggui Niantong Decoction on the basis of control group for 4 weeks.The clinical efficacy,TCM symptom score,VAS scale score,NDI questionnaire,CASCS scale score,serum inflammatory indicators IL-1β,IL-6β,TNF-αlevel and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of experimental group after treatment was significantly higher than that of control group(P<0.05).After treatment,TCM symptom score of two groups was significantly decreased,and the test group was lower than the control group(P<0.05).VAS and NDI scores after treatment were lower than before treatment,CASCS scores were higher than before treatment,and the change range of experimental group was higher than that of control group(P<0.05).The serum levels of IL-1β,IL-6βand TNF-αin 2 groups after treatment were lower than before treatment,and the experimental group was lower than the control group(P<0.05).Conclusion:Danggui Niantong Decoction combined with celecxib has a good effect in the treatment of cervical spondylopathy patients with rheumatic heat arthralgia nerve root type,which can significantly improve cervical spine function and clinical symptoms,reduce the level of pain and inflammatory factors,and is safe,worthy of clinical promotion.关键词
当归拈痛汤/风湿热痹/神经根型颈椎病/塞来昔布Key words
Danggui Niantong Decoction/Wind-Damp-Heat obstruction syndrome/Cervical spondylotic radiculopathy/Celecoxib分类
医药卫生引用本文复制引用
艾柯,王雷,杨军,陈杰能..当归拈痛汤联合塞来昔布治疗风湿热痹型神经根型颈椎病的临床观察[J].中医药学报,2026,54(7):103-108,6.基金项目
湖北省自然科学基金项目(2021CFB530) （2021CFB530）
