组织工程与重建外科杂志2026，Vol.22Issue(3)：324-329,6.DOI:10.3969/j.issn.1673-0364.2026.03.016
重组Ⅲ型人源化胶原蛋白的应用进展
Research advances in the applications of recombinant humanized collagen type Ⅲ
周小婷 1韩颖 1魏聪 1周岩 1周静 1徐玉茵1
作者信息
- 1. 450000 河南省郑州市 河南省药品医疗器械检验院(河南省疫苗批签中心)
- 折叠
摘要
Abstract
Recombinant humanized collagen is a full-length or partial amino acid sequence fragment encoded by a specific type of human collagen gene prepared by DNA recombination technology,or a combination containing human collagen functional fragments.Type Ⅲ collagen is a triple helix protein consisting of three identical α1 chains,encoded by the COL3A1 gene.Recombinant Ⅲ type humanized collagen(RHC Ⅲ)has shown great potential for application in medical devices due to its good biological compatibility,cell adhesion,and functions of promoting new cell formation and cell growth.This article mainly focuses on the research and application status of RHC Ⅲ in the fields of tissue regeneration,medical cosmetology,immunotherapy,etc.,and makes prospects for the future development and application prospects of recombinant collagen.关键词
重组人源化胶原蛋白/Ⅲ型胶原蛋白/组织再生/医疗美容/免疫疗法Key words
Recombinant humanized collagen protein/Type Ⅲ collagen/Tissue regeneration/Medical cosmetology/Immunotherapy分类
医药卫生引用本文复制引用
周小婷,韩颖,魏聪,周岩,周静,徐玉茵..重组Ⅲ型人源化胶原蛋白的应用进展[J].组织工程与重建外科杂志,2026,22(3):324-329,6.
