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Pervasive environmental contaminant acrolein compromises myocardial geometry and function through the induction of cuproptosis

Xiaohu Wang Shuyi Zhu Yipin Zhao Xinlong Di Lingfei Cao Russel JReiter Emily YHe Yuan Zhou Bonglee Kim Yong Cheng Jun Ren

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(3)：P.541-550,10.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(3)：P.541-550,10.DOI:10.3724/abbs.2025179

Pervasive environmental contaminant acrolein compromises myocardial geometry and function through the induction of cuproptosis

Xiaohu Wang ¹Shuyi Zhu ²Yipin Zhao ³Xinlong Di ⁴Lingfei Cao ⁵Russel JReiter ⁶Emily YHe ⁷Yuan Zhou ⁸Bonglee Kim ⁹Yong Cheng ¹⁰Jun Ren¹¹

作者信息

1. Department of Cardiology,Fuwai Central China Cardiovascular Hospital,Henan Provincial People''s Hospital Heart Center,Zhengzhou 451464,China
2. The Cardiovascular Medicine Department,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 451162,China
3. Department of Cardiology,Zhengzhou University Central China Fuwai Hospital,Zhengzhou 451464,China
4. Department of Cardiology,The Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China
5. Henan Key Laboratory of Medical Tissue Regeneration,Henan Medical University,Xinxiang 453003,China
6. Department of Cell Systems and Anatomy,UT Health San Antonio,TX,USA
7. Department of Clinical Immunology,Xijing Hospital,Air Force Medical University,Xi''an 710032,China
8. Department of Biomedical Informatics,School of Basic Medical Sciences,Peking University,Beijing 100191,China
9. Department of Pathology,College of Korean Medicine,Kyung Hee University,Hoegidong Dongdaemun-gu,Seoul 02447,Republic of Korea
10. Department of Cardiovascular Medicine,The Sixth People''s Hospital of Zhengzhou,Zhengzhou 450052,China
11. Department of Cardiology,Zhongshan Hospital Fudan University,Shanghai 200032,China Shanghai Institute of Cardiovascular Diseases,Zhongshan Hospital Fudan University,Shanghai 200032,China National Clinical Research Center for Interventional Medicine,Shanghai 200032,China
折叠

摘要

关键词

acrolein/myocardial/remodeling/function/cuproptosis/MTF2

分类

医药卫生

引用本文复制引用

Xiaohu Wang,Shuyi Zhu,Yipin Zhao,Xinlong Di,Lingfei Cao,Russel JReiter,Emily YHe,Yuan Zhou,Bonglee Kim,Yong Cheng,Jun Ren..Pervasive environmental contaminant acrolein compromises myocardial geometry and function through the induction of cuproptosis[J].Acta Biochimica et Biophysica Sinica,2026,58(3):P.541-550,10.

基金项目

supported in part by the grants from the Henan Provincial Science and Technology Research Project(No.25202310242) （No.25202310242）

the Henan Provincial Science and Technology Research Project(No.222102310487) （No.222102310487）

the Henan Provincial Medical Science and Technology Tackling Program(No.LHGJ20240150). （No.LHGJ20240150）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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