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Quinolone tolerance in Escherichia coli dueto defects in the adenosine ribonucleotides de novo biosynthesis pathway

Weiwei Zhu Yuejuan Nong Jie Su Jingwen Yang Lina Ma Yunxin Xue Dai Wang Jianjun Niu Karl Drlica Xilin Zhao

mLife2026，Vol.5Issue(2)：P.217-228,12.

mLife2026，Vol.5Issue(2)：P.217-228,12.DOI:10.1002/mlf2.70059

Quinolone tolerance in Escherichia coli dueto defects in the adenosine ribonucleotides de novo biosynthesis pathway

Weiwei Zhu ¹Yuejuan Nong ¹Jie Su ¹Jingwen Yang ¹Lina Ma ¹Yunxin Xue ¹Dai Wang ¹Jianjun Niu ²Karl Drlica ³Xilin Zhao¹

作者信息

1. State Key Laboratory of Vaccines for Infectious Diseases,Xiang-An Biomedicine Laboratory,National Innovation Platform for Industry-Education Integration in Vaccine Research,Department of Laboratory Medicine,School of Public Health,Xiamen University,Xiamen,China
2. Center of Clinical Laboratory,Zhongshan Hospital,School of Medicine,Xiamen University,Xiamen,China
3. Public Health Research Institute and Department of Microbiology,Biochemistry&Molecular Genetics,New Jersey Medical School,Rutgers University,Newark,New Jersey,USA
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摘要

关键词

adenosine ribonucleotides de novo biosynthesis/AMP/antibiotic tolerance/PurA/PurB/ROS

分类

医药卫生

引用本文复制引用

Weiwei Zhu,Yuejuan Nong,Jie Su,Jingwen Yang,Lina Ma,Yunxin Xue,Dai Wang,Jianjun Niu,Karl Drlica,Xilin Zhao..Quinolone tolerance in Escherichia coli dueto defects in the adenosine ribonucleotides de novo biosynthesis pathway[J].mLife,2026,5(2):P.217-228,12.

基金项目

supported in part by the grants from the National Natural Science Foundation of China(82172316 and 8147325) （82172316 and 8147325）

the Scientific Research Foundation of the State Key Laboratory of Vaccines for Infectious Diseases,Xiang-An Biomedicine Laboratory(2023XAKJ0101022) （2023XAKJ0101022）

XMU Training Program of Innovation and Entrepreneurship for Undergraduates(S202410384488). （S202410384488）

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ISSN：2097-1699

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