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Genome-wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

Zhenfang Mei Yawen Cai Jianfeng Huang Kedong Zhao Zuqin Zhang Dandan Yu Shiyan Lu Zeying Lai Thomas K.Wood Xinmiao Fu

mLife2026，Vol.5Issue(2)：P.180-198,19.

mLife2026，Vol.5Issue(2)：P.180-198,19.DOI:10.1002/mlf2.70072

Genome-wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters

Zhenfang Mei ¹Yawen Cai ²Jianfeng Huang ¹Kedong Zhao ²Zuqin Zhang ²Dandan Yu ¹Shiyan Lu ¹Zeying Lai ¹Thomas K.Wood ³Xinmiao Fu²

作者信息

1. Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation,College of Life Sciences,Fujian Normal University,Fuzhou,China
2. Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation,College of Life Sciences,Fujian Normal University,Fuzhou,China Institute of Precision Medicine,Fujian Provincial Hospital,Fuzhou University Affiliated Provincial Hospital,Fuzhou,China
3. Department of Chemical Engineering,Pennsylvania State University,University Park,Pennsylvania,USA
折叠

摘要

关键词

antibiotic uptake/ATP/ciprofloxacin/persister/ROS

分类

医药卫生

引用本文复制引用

Zhenfang Mei,Yawen Cai,Jianfeng Huang,Kedong Zhao,Zuqin Zhang,Dandan Yu,Shiyan Lu,Zeying Lai,Thomas K.Wood,Xinmiao Fu..Genome-wide screen reveals a universal role of ATP in ciprofloxacin tolerance among genetically distinct Escherichia coli persisters[J].mLife,2026,5(2):P.180-198,19.

基金项目

supported by the grants from the National Natural Science Foundation of China(No.82372295 to X.F.) （No.82372295 to X.F.）

the Innovation Star of Fujian Province(to X.F.). （to X.F.）

mLife

ISSN：2097-1699

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