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Structural basis for suramin binding to the C-terminal domain of the SARS-CoV-2 nucleocapsid protein

Chenyun Guo Xiao Li Hao Xu Jiaxin Yu Jia Li Donghai Lin

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(4)：P.911-919,9.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(4)：P.911-919,9.DOI:10.3724/abbs.2025182

Structural basis for suramin binding to the C-terminal domain of the SARS-CoV-2 nucleocapsid protein

Chenyun Guo ¹Xiao Li ¹Hao Xu ¹Jiaxin Yu ¹Jia Li ¹Donghai Lin¹

作者信息

1. Key Laboratory for Chemical Biology of Fujian Province,College of Chemistry and Chemical Engineering,Xiamen University,Xiamen 361005,China
折叠

摘要

关键词

NMR spectroscopy/nucleocapsid C-terminal domain(N-CTD)/RNA-protein interaction/SARS-CoV-2/suramin

分类

医药卫生

引用本文复制引用

Chenyun Guo,Xiao Li,Hao Xu,Jiaxin Yu,Jia Li,Donghai Lin..Structural basis for suramin binding to the C-terminal domain of the SARS-CoV-2 nucleocapsid protein[J].Acta Biochimica et Biophysica Sinica,2026,58(4):P.911-919,9.

基金项目

supported by the grants from the Natural Science Foundation of Xiamen,China(No.3502Z202473031) （No.3502Z202473031）

the Natural Science Foundation of Fujian Province(No.2020J01022) （No.2020J01022）

the National Natural Science Foundation of China(No.32271496). （No.32271496）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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