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Intestinal epithelial C/EBPβ deficiency impairs colitis-associated tumorigenesis by disrupting CXCL1/CXCL2/CXCL5-CXCR2-mediated neutrophil infiltration

Mingyue Li Xintong Wang Wenjie Hu Xiaohui Cheng Qi Sun Yongjie Wu Zhen Huang Jiangning Chen

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(4)：P.882-894,13.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(4)：P.882-894,13.DOI:10.3724/abbs.2025119

Intestinal epithelial C/EBPβ deficiency impairs colitis-associated tumorigenesis by disrupting CXCL1/CXCL2/CXCL5-CXCR2-mediated neutrophil infiltration

Mingyue Li ¹Xintong Wang ¹Wenjie Hu ¹Xiaohui Cheng ¹Qi Sun ¹Yongjie Wu ¹Zhen Huang ²Jiangning Chen³

作者信息

1. State Key Laboratory of Analytical Chemistry for Life Sciences,School of Life Sciences,Nanjing University,Nanjing 210023,China
2. State Key Laboratory of Analytical Chemistry for Life Sciences,School of Life Sciences,Nanjing University,Nanjing 210023,China State Key Laboratory of Pharmaceutical Biotechnology,School of Life Sciences,Nanjing University,Nanjing 210023,China NJU Xishan Institute of Applied Biotechnology,Wuxi 214101,China
3. State Key Laboratory of Analytical Chemistry for Life Sciences,School of Life Sciences,Nanjing University,Nanjing 210023,China State Key Laboratory of Pharmaceutical Biotechnology,School of Life Sciences,Nanjing University,Nanjing 210023,China
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摘要

关键词

colitis-associated tumorigenesis/epithelial-specific C/EBPβ/CXCL1/CXCL2/CXCL5-CXCR2 axis/CXCR2-mediated neutrophil infiltration

分类

医药卫生

引用本文复制引用

Mingyue Li,Xintong Wang,Wenjie Hu,Xiaohui Cheng,Qi Sun,Yongjie Wu,Zhen Huang,Jiangning Chen..Intestinal epithelial C/EBPβ deficiency impairs colitis-associated tumorigenesis by disrupting CXCL1/CXCL2/CXCL5-CXCR2-mediated neutrophil infiltration[J].Acta Biochimica et Biophysica Sinica,2026,58(4):P.882-894,13.

基金项目

supported by the grants from the National Natural Science Foundation of China(Nos.31771550,31870821 and 81972267) （Nos.31771550,31870821 and 81972267）

the Jiangsu Provincial Science and Technology Plan Special Fund(No.BM2023008). （No.BM2023008）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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