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P300-mediated H3K18 acetylation triggers necroptosis via modulation of KRT18 transcription in diabetic nephropathy

Qiao Zhao Qinqin Cai Aynigar Nizam Qingxia Yang Xu Liu Fufen Meng Zhipeng Meng

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(4)：P.854-864,11.

Acta Biochimica et Biophysica Sinica2026，Vol.58Issue(4)：P.854-864,11.DOI:10.3724/abbs.2026015

P300-mediated H3K18 acetylation triggers necroptosis via modulation of KRT18 transcription in diabetic nephropathy

Qiao Zhao ¹Qinqin Cai ²Aynigar Nizam ¹Qingxia Yang ¹Xu Liu ³Fufen Meng ¹Zhipeng Meng³

作者信息

1. Department of Anesthesiology,The 3rd Affiliated Teaching Hospital of Xinjiang Medical University(Affiliated Cancer Hospital),Urumqi 830000,China
2. Department of Anesthesiology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 20008,China
3. Department of Anesthesiology,Huzhou Central Hospital,Affiliated Central Hospital of Huzhou University,Huzhou 313000,China
折叠

摘要

关键词

P300/H3K18ac/histone acetylation/KRT18/necroptosis/diabetic nephropathy

分类

医药卫生

引用本文复制引用

Qiao Zhao,Qinqin Cai,Aynigar Nizam,Qingxia Yang,Xu Liu,Fufen Meng,Zhipeng Meng..P300-mediated H3K18 acetylation triggers necroptosis via modulation of KRT18 transcription in diabetic nephropathy[J].Acta Biochimica et Biophysica Sinica,2026,58(4):P.854-864,11.

基金项目

supported by the grants from the Tianshan Talent Program for High-Level Personnel Training in Medicine and Health(No.TSYC202301B040) （No.TSYC202301B040）

the Key Research and Development Program Project of Xinjiang Uygur Autonomous Region(No.2022B03009-4). （No.2022B03009-4）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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