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Wuhuang Zhizi Decoction promotes diabetic foot ulcer healing via SIRT1/Nrf2-dependent M2 polarization and gut-immune modulation

Rui-Fei Liu Yu-Chen Shi Lian-Heng Xia Jie Gao

Traditional Medicine Research2026，Vol.11Issue(11)：P.27-39,13.

Traditional Medicine Research2026，Vol.11Issue(11)：P.27-39,13.DOI:10.53388/TMR20251126002

Wuhuang Zhizi Decoction promotes diabetic foot ulcer healing via SIRT1/Nrf2-dependent M2 polarization and gut-immune modulation

Rui-Fei Liu ¹Yu-Chen Shi ²Lian-Heng Xia ³Jie Gao³

作者信息

1. Graduate School,Heilongjiang University of Chinese Medicine,Harbin 150081,China
2. Department of Clinical Medicine,Jinhua Vocational and Technical University School of Medicine,Jinhua 321017,China
3. Department of Peripheral Vascular,The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150081,China
折叠

摘要

关键词

diabetic foot ulcer/Wuhuang Zhizi Decoction/SIRT1/Nrf2/macrophage polarization/inflammation

分类

医药卫生

引用本文复制引用

Rui-Fei Liu,Yu-Chen Shi,Lian-Heng Xia,Jie Gao..Wuhuang Zhizi Decoction promotes diabetic foot ulcer healing via SIRT1/Nrf2-dependent M2 polarization and gut-immune modulation[J].Traditional Medicine Research,2026,11(11):P.27-39,13.

基金项目

funded by the National Natural Science Foundation of China(NSFC),(grant number 82305253) （NSFC）

Postdoctoral Science Foundation Project of Heilongjiang Province(grant number LBH-Z24090) （grant number LBH-Z24090）

China Postdoctoral Science Foundation(grant number 2025MD774056). （grant number 2025MD774056）

Traditional Medicine Research

ISSN：2413-3973

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