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Pien Tze Huang exerts anti-tumor effect by promoting CSF-1R degradation and cleavage in tumor-associated macrophages

Jun-Jie Zhang Han-Shi Guo Jing-Na Yuan Si-Yu Chen Bei Li Shi-Cong Wang Chun-Dong Yu Yi-Lin Hong

Traditional Medicine Research2026，Vol.11Issue(11)：P.14-26,13.

Traditional Medicine Research2026，Vol.11Issue(11)：P.14-26,13.DOI:10.53388/TMR20260311003

Pien Tze Huang exerts anti-tumor effect by promoting CSF-1R degradation and cleavage in tumor-associated macrophages

Jun-Jie Zhang ¹Han-Shi Guo ²Jing-Na Yuan ²Si-Yu Chen ³Bei Li ⁴Shi-Cong Wang ⁵Chun-Dong Yu ²Yi-Lin Hong¹

作者信息

1. Xiamen Key Laboratory of Traditional Chinese Medicine Bio-engineering,School of Pharmacy,Xiamen Medical College,Fujian 361023,China State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,China
2. State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Biology,School of Life Sciences,Xiamen University,Fujian 361104,China
3. College of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine,Fujian 350122,China
4. Ordos Center for Disease Control and Prevention,Ordos,Inner Mongolia Autonomous Region 017010,China
5. Fujian Pien Tze Huang Enterprise Key Laboratory of Natural Medicine Research and Development,Fujian 363000,China
折叠

摘要

关键词

Pien Tze Huang/colorectal cancer/tumor-associated macrophages/CSF-1R/TLR2-iRhom2-ADAM17/immunotherapy

分类

医药卫生

引用本文复制引用

Jun-Jie Zhang,Han-Shi Guo,Jing-Na Yuan,Si-Yu Chen,Bei Li,Shi-Cong Wang,Chun-Dong Yu,Yi-Lin Hong..Pien Tze Huang exerts anti-tumor effect by promoting CSF-1R degradation and cleavage in tumor-associated macrophages[J].Traditional Medicine Research,2026,11(11):P.14-26,13.

基金项目

funding from the Natural Science Foundation of Fujian Province of China(No.2025J08328 （）

2023J01249) （）

the Natural Science Foundation of Xiamen Municipality(No.3502Z202571070) （No.3502Z202571070）

Zhangzhou Pien Tze Huang Pharmaceutical Co.Ltd(No.YHT-21036-N-2102). （No.YHT-21036-N-2102）

Traditional Medicine Research

ISSN：2413-3973

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