Oncology Research2026，Vol.34Issue(6)：P.457-470,14.DOI:10.32604/or.2026.076384
Impact of Germline BRCA1/2 Mutations on Clinical Outcomes in Metastatic Triple-Negative Breast Cancer Patients Treated with Sacituzumab Govitecan—An International CEBCC Study from Poland,the Czech Republic and Slovakia
Renata Pacholczak-Madej 1Mirosława Püsküllüoğlu 2Anna Polakiewicz-Gilowska 3Małgorzata Pieniążek 4Iveta Kolářová 5Miroslava Malejčíková 6Lenka Rušinová 7MilošHolánek 8Renata Soumarová 9Karolina Winsko-Szczęsnowicz 10JustynaŻubrowska 11Aleksandra Konieczna 12Agnieszka Młodzińska 12Daniel Krejčí 13Iwona Danielewicz 14Magdalena Szymanik-Resko 14Tomasz Ciszewski 15Maja Lisik-Habib 16Anika Pękala 16HanaŠtudentová 17JanŠustr 18Bogumiła Czartoryska-Arłukowicz 10AleksandraŁacko 4Jolanta Smok-Kalwat 11MichałJarząb 3Zuzana Bielčiková 19Marcin Kubeczko3
作者信息
- 1. Department of Gynecological Oncology,Maria Sklodowska-Curie National Research Institute of Oncology,Kraków Branch,Kraków,Poland Department of Anatomy,Jagiellonian University Medical College,Krakow,Poland
- 2. Department of Clinical Oncology,Maria Sklodowska-Curie National Research Institute of Oncology,Kraków Branch,Kraków,Poland
- 3. Breast Cancer Center,Maria Sklodowska-Curie National Research Institute of Oncology,Gliwice,Poland
- 4. Lower Silesian Comprehensive Cancer Center,Wrocław Medical University,Wrocław,Poland
- 5. Department of Oncology and Radiotherapy,Faculty of Medicine in Hradec Královéand University Hospital in Hradec Králové,Charles University,Hradec Králové,Czech Republic
- 6. Oncology Clinic of LFUK,National Cancer Institute,Bratislava,Slovakia
- 7. Department of Oncology,Stefan Kukura Hospital Michalovce,Michalovce,Slovakia
- 8. Department of Comprehensive Cancer Care,Faculty of Medicine,Masaryk University,and Masaryk Memorial Cancer Institute,Brno,Czech Republic
- 9. Department of Oncology,Third Faculty of Medicine,Charles University,University Hospital KralovskéVinohrady,Prague,Czech Republic
- 10. Department of Clinical Oncology,Maria Sklodowska-Curie Bialystok Oncology Center,Białystok,Poland
- 11. Department of Clinical Oncology,Holy Cross Cancer Center,Kielce,Poland
- 12. Department of Breast Cancer and Reconstructive Surgery,Maria Sklodowska-Curie National Research Institute of Oncology,Warsaw,Poland
- 13. Department of Oncology,First Faculty of Medicine,Charles University in Prague,and Bulovka University Hospital,Prague,Czech Republic
- 14. Department of Oncology and Radiotherapy,Szpitale Pomorskie sp.z o.o.,Gdynia,Poland
- 15. Department of Metabolic Diseases and Immuno-Oncology,Medical University of Lublin,Lublin,Poland
- 16. Department of Proliferative Diseases,Nicolaus Copernicus Multidisciplinary Centre for Oncology and Traumatology,Lodz,Poland
- 17. Department of Oncology,Faculty of Medicine and Dentistry,Palacky University and University Hospital,Olomouc,Czech Republic
- 18. Department of Oncology and Radiotherapy,Faculty of Medicine in Pilsen,Charles University,and University Hospital Pilsen,Plzen,Czech Republic
- 19. Department of Oncology,First Faculty of Medicine,Charles University,and General University Hospital,Prague,Czech Republic
- 折叠
摘要
关键词
Triple-negative breast cancer/sacituzumab govitecan/BRCA1/2 germline mutations/real-world evidence/international multicenter cohort分类
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Renata Pacholczak-Madej,Mirosława Püsküllüoğlu,Anna Polakiewicz-Gilowska,Małgorzata Pieniążek,Iveta Kolářová,Miroslava Malejčíková,Lenka Rušinová,MilošHolánek,Renata Soumarová,Karolina Winsko-Szczęsnowicz,JustynaŻubrowska,Aleksandra Konieczna,Agnieszka Młodzińska,Daniel Krejčí,Iwona Danielewicz,Magdalena Szymanik-Resko,Tomasz Ciszewski,Maja Lisik-Habib,Anika Pękala,HanaŠtudentová,JanŠustr,Bogumiła Czartoryska-Arłukowicz,AleksandraŁacko,Jolanta Smok-Kalwat,MichałJarząb,Zuzana Bielčiková,Marcin Kubeczko..Impact of Germline BRCA1/2 Mutations on Clinical Outcomes in Metastatic Triple-Negative Breast Cancer Patients Treated with Sacituzumab Govitecan—An International CEBCC Study from Poland,the Czech Republic and Slovakia[J].Oncology Research,2026,34(6):P.457-470,14.
