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A natural five-amino-acid insert at the S2’cleavage site of MERS-CoV spike enhances viral membrane fusion

Guimin Dai Wenjie Chen Wenying Cao Guigen Zhang

Virologica Sinica2026，Vol.41Issue(2)：P.485-489,5.

Virologica Sinica2026，Vol.41Issue(2)：P.485-489,5.DOI:10.1016/j.virs.2026.04.006

A natural five-amino-acid insert at the S2’cleavage site of MERS-CoV spike enhances viral membrane fusion

Guimin Dai ¹Wenjie Chen ¹Wenying Cao ¹Guigen Zhang¹

作者信息

1. Institute of Human Virology,Department of Pathogen Biology and Biosecurity,and Key Laboratory of Tropical Disease Control of Ministry of Education,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou,510080,China
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摘要

关键词

natural insert/viral membrane fusion/five amino acid/S cleavage site/spike protein/covs/MERS COV/coronaviruses

分类

医药卫生

引用本文复制引用

Guimin Dai,Wenjie Chen,Wenying Cao,Guigen Zhang..A natural five-amino-acid insert at the S2’cleavage site of MERS-CoV spike enhances viral membrane fusion[J].Virologica Sinica,2026,41(2):P.485-489,5.

基金项目

supported by the grants from the innovative R&D team project of“The Pearl River Talent Recruitment Program”(2021ZT09Y544) （2021ZT09Y544）

the National Natural Science Foundation of China(82072283,82341059)to Z.G. （82072283,82341059）

Virologica Sinica

ISSN：1674-0769

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