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Metatranscriptomics uncovers host immune and microbiome signatures specific to and shared between human metapneumovirus and respiratory syncytial virus infections in children

Hongwei Zhao Ju Yin Yingdong Dong Qianyu Feng Huifang Liu Shuaibing Han Zhengde Xie Lili Xu

Virologica Sinica2026，Vol.41Issue(2)：P.276-292,17.

Virologica Sinica2026，Vol.41Issue(2)：P.276-292,17.DOI:10.1016/j.virs.2026.03.002

Metatranscriptomics uncovers host immune and microbiome signatures specific to and shared between human metapneumovirus and respiratory syncytial virus infections in children

Hongwei Zhao ¹Ju Yin ²Yingdong Dong ¹Qianyu Feng ¹Huifang Liu ³Shuaibing Han ¹Zhengde Xie ¹Lili Xu¹

作者信息

1. Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children,National Clinical Research Center for Respiratory Diseases,National Key Discipline of Pediatrics(Capital Medical University),Beijing Research Center for Respiratory Infectious Diseases,Beijing Pediatric Research Institute,Beijing Children''s Hospital,Capital Medical University,National Center for Children''s Health,Beijing 100045,China Research Unit of Critical Infection in Children,Chinese Academy of Medical Sciences,2019RU016,Beijing 100045,China
2. Department of Respiratory,National Clinical Research Center for Respiratory Diseases,Beijing Children''s Hospital,Capital Medical University,National Center for Children''s Health,Beijing 100045,China
3. Vision Medical Center for Infectious Diseases,Guangzhou 510300,China
折叠

摘要

关键词

Human metapneumovirus(hMPV)/Respiratory syncytial virus(RSV)/Host immune profile/Microbiome

分类

医药卫生

引用本文复制引用

Hongwei Zhao,Ju Yin,Yingdong Dong,Qianyu Feng,Huifang Liu,Shuaibing Han,Zhengde Xie,Lili Xu..Metatranscriptomics uncovers host immune and microbiome signatures specific to and shared between human metapneumovirus and respiratory syncytial virus infections in children[J].Virologica Sinica,2026,41(2):P.276-292,17.

基金项目

funded by the Beijing Research Center for Respiratory Infectious Diseases Project(BJRID2025-008) （BJRID2025-008）

the Beijing Natural Science Foundation(5242007,L222076) （5242007,L222076）

the High-level Public Health Technical Talents Project by the Beijing Municipal Commission of Health(Key discipline personnel-02-05) （Key discipline personnel-02-05）

the Reform and Development of the Beijing Municipal Health Commission,and the Respiratory Research Project of the National Clinical Research Center for Respiratory Diseases(HXZX-202106). （HXZX-202106）

Virologica Sinica

ISSN：1674-0769

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