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Dynamic exchange strategy for enzyme immobilization in Zr-based metal-organic frameworks for green synthesis of β-lactam antibiotics

Heng Hu Shaochun Wu Yunlong Zheng Zhenjie Zhang Mingfang Yang Yao Chen

Green Chemical Engineering2026，Vol.7Issue(4)：P.389-398,10.

Green Chemical Engineering2026，Vol.7Issue(4)：P.389-398,10.DOI:10.1016/j.gce.2025.03.001

Dynamic exchange strategy for enzyme immobilization in Zr-based metal-organic frameworks for green synthesis of β-lactam antibiotics

Heng Hu ¹Shaochun Wu ¹Yunlong Zheng ¹Zhenjie Zhang ²Mingfang Yang ¹Yao Chen³

作者信息

1. Key Laboratory of Biopharmaceutical Preparation and Delivery,State Key Laboratory of Biochemical Engineering,Institute of Process Engineering,Chinese Academy of Sciences,Beijing,100190,China
2. College of Chemistry,Nankai University,Tianjin,300071,China
3. Key Laboratory of Biopharmaceutical Preparation and Delivery,State Key Laboratory of Biochemical Engineering,Institute of Process Engineering,Chinese Academy of Sciences,Beijing,100190,China State Key Laboratory of Medicinal Chemical Biology,College of Pharmacy,Nankai University,Tianjin,300071,China Haihe Laboratory of Synthetic Biology,Tianjin,300308,China Frontiers Science Center for Cell Responses,Nankai University,Tianjin,300071,China
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摘要

关键词

Enzyme immobilization/Metal-organic frameworks/Dynamic exchange strategy/Enzyme catalysis/β-Lactam antibiotic

分类

化学化工

引用本文复制引用

Heng Hu,Shaochun Wu,Yunlong Zheng,Zhenjie Zhang,Mingfang Yang,Yao Chen..Dynamic exchange strategy for enzyme immobilization in Zr-based metal-organic frameworks for green synthesis of β-lactam antibiotics[J].Green Chemical Engineering,2026,7(4):P.389-398,10.

基金项目

supported by financial support from the National Key Research and Development Program of China (2021YFC2102100) （2021YFC2102100）

Haihe Laboratory of Synthetic Biology (22HHSWSS00008) （22HHSWSS00008）

the National Natural Science Foundation of China (22371136) （22371136）

China Postdoctoral Science Foundation (General Program, 2022M721700)。（General Program, 2022M721700）

Green Chemical Engineering

ISSN：2096-9147

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