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Loss of PTH 1 receptor signaling in periodontal cells drives cementum dysfunction and molar ankylosis in mice

Hakan Turkkahraman Carson Joseph Walton Tianli Zhu Nisreen Akel Silvia Marino Xue Yuan Teresita M.Bellido

Bone Research2026，Vol.14Issue(3)：P.892-901,10.

Bone Research2026，Vol.14Issue(3)：P.892-901,10.DOI:10.1038/s41413-026-00533-5

Loss of PTH 1 receptor signaling in periodontal cells drives cementum dysfunction and molar ankylosis in mice

Hakan Turkkahraman ¹Carson Joseph Walton ²Tianli Zhu ³Nisreen Akel ⁴Silvia Marino ⁴Xue Yuan ⁵Teresita M.Bellido⁶

作者信息

1. Department of Orthodontics and Oral Facial Genetics,Indiana University School of Dentistry,Indianapolis,IN,USA
2. Department of Otolaryngology-Head&Neck Surgery,Indiana University School of Medicine,Indianapolis,IN,USA
3. Department of Biomedical Sciences and Comprehensive Care,Indiana University School of Dentistry,Indianapolis,IN,USA
4. Department of Physiology and Cell Biology,University of Arkansas for Medical Sciences,Little Rock,AR,USA
5. Department of Otolaryngology-Head&Neck Surgery,Indiana University School of Medicine,Indianapolis,IN,USA Indiana Center for Musculoskeletal Health,Indiana University School of Medicine,Indianapolis,IN,USA
6. Department of Physiology and Cell Biology,University of Arkansas for Medical Sciences,Little Rock,AR,USA Central Arkansas Veterans Healthcare System,John L.McClellan,Little Rock,AR,USA
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摘要

关键词

mineral ion homeostasis/craniofacial/cementum dysfunction/tooth root formation eruption/craniofacial alterationsincluding/skeletal developmentalthough/PTH R/craniofacial integrity

分类

医药卫生

引用本文复制引用

Hakan Turkkahraman,Carson Joseph Walton,Tianli Zhu,Nisreen Akel,Silvia Marino,Xue Yuan,Teresita M.Bellido..Loss of PTH 1 receptor signaling in periodontal cells drives cementum dysfunction and molar ankylosis in mice[J].Bone Research,2026,14(3):P.892-901,10.

基金项目

supported by the National Institute of Dental and Craniofacial Research(R03DE033059 to X.Y.) （R03DE033059 to X.Y.）

the Veterans Administration(I01 BX002104 and IK6BX004596 to T.B.) （I01 BX002104 and IK6BX004596 to T.B.）

the National Institutes of Arthritis and Musculoskeletal and Skin Diseases(R01-AR059357 to T.B.) （R01-AR059357 to T.B.）

the UAMS College of Medicine Sturgis Endowment Grant （）

the Arkansas Research Alliance. （）

Bone Research

ISSN：2095-4700

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