海南医科大学学报2026，Vol.32Issue(13)：1034-1040,7.DOI:10.13210/j.cnki.jhmu.20251216.002
无乳链球菌黏附因子及靶向干预研究进展
Research progress on adhesion factors and targeted intervention of Streptococcus agalactiae
摘要
Abstract
Streptococcus agalactiae(GBS)is a Gram-positive conditional pathogen that commonly colonizes the urogenital and gastrointestinal tracts.It can cause infections and even death in perinatal mothers,newborns,elderly individuals,and those with compromised immune systems.During the process of colonizing and infecting the host,GBS first needs to adhere to the host cells by binding to the receptors on the surface of the host cells through adhesion factors,this is an important prerequisite for GBS's subsequent colonization,invasion,and pathogenesis.This review offers a comprehensive review of the pathogenic process and in-tervention strategies facilitated by GBS adhesion factors,spanning from molecular mechanisms to clinical applications.The objec-tive is to furnish a more definitive theoretical foundation for the prevention and management of GBS infections.关键词
无乳链球菌/黏附因子/致病机制/感染/研究进展Key words
Streptococcus agalactiae/Adhesion factor/Pathogenic mechanism/Infection/Research progress分类
医药卫生引用本文复制引用
田陈燕,陈惠滢,龚护民..无乳链球菌黏附因子及靶向干预研究进展[J].海南医科大学学报,2026,32(13):1034-1040,7.基金项目
This study was supported by the Key Research and Development Projects in Hainan Province(ZDYF2024SHFZ093) （ZDYF2024SHFZ093）
Graduate Student Innovation Research Project of Hainan Medical University(HYYB2023A43) 海南省重点研发项目(ZDYF2024SHFZ093) （HYYB2023A43）
海南医学院研究生创新科研课题(HYYB2023A43) （HYYB2023A43）
