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强迫振荡肺功能测试的呼吸电抗校准方法

刘秉鑫 王梦源 林俊杰 刘志朋 殷涛 张顺起

生物医学工程研究2026,Vol.45Issue(3):221-226,6.
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生物医学工程研究2026,Vol.45Issue(3):221-226,6.DOI:10.19529/j.cnki.1672-6278.2026.03.06

强迫振荡肺功能测试的呼吸电抗校准方法

Method for calibrating respiratory reactance based on the forced oscillation pulmonary function test

刘秉鑫 1王梦源 1林俊杰 1刘志朋 1殷涛 1张顺起1

作者信息

  • 1. 中国医学科学院北京协和医学院生物医学工程研究所,先进医用材料与医疗器械全国重点实验室,天津市神经调控与修复重点实验室,天津医学健康科学研究院,呼吸与危重症诊疗技术与器械教育部工程研究中心,天津 300192
  • 折叠

摘要

Abstract

Forced oscillation technique(FOT)is a critical tool in pulmonary function testing.Aiming at the lack of a unified standard for electrical reactance in existing FOT equipment,which leads to significant differences in the electrical reactance results of different instruments,we proposed an easily reproducible design method for reactance standards that covers the human physiological range selected commercial FOT devices(e.g.,Canadian Thorasys tremoflo® C2,German Jaeger IOS)to test these standards and recor-ded absolute errors for each instrument.Furthermore,5 healthy subjects were recruited for validation tests.The results showed that cali-bration based on theoretical values significantly reduced the individual differences among the instruments for the same subjects,with an average reduction of 51.4%in standard deviation during the test.This method can lay a foundation for cross-device data interoperability and clinical standardization.

关键词

呼吸电抗/校准方法/强迫振荡技术/肺功能测试/傅里叶变换/电抗标准物

Key words

Respiratory reactance/Calibration method/Forced oscillation technique/Pulmonary function test/Fourier transform/Reactance standards

分类

医药卫生

引用本文复制引用

刘秉鑫,王梦源,林俊杰,刘志朋,殷涛,张顺起..强迫振荡肺功能测试的呼吸电抗校准方法[J].生物医学工程研究,2026,45(3):221-226,6.

基金项目

中国医学科学院医学与健康科技创新工程项目(2024-I2M-ZH-019) (2024-I2M-ZH-019)

国家自然科学基金重大科研仪器研制项目(81927806) (81927806)

国家自然科学基金面上项目(61871406). (61871406)

生物医学工程研究

1672-6278

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