河南中医2026，Vol.46Issue(8)：1193-1197,5.DOI:10.16367/j.issn.1003-5028.2026.08.0194
中医药调控下丘脑-垂体-肾上腺轴改善应激反应治疗急性高原病的作用机制
Mechanisms of Traditional Chinese Medicine in Treating Acute Mountain Sickness by Regulating the Hypothalamic-Pituitary-Adrenal Axis to Improve Stress Response
摘要
Abstract
The occurrence of acute mountain sickness is closely related to the hypoxic conditions in high-altitude environment,particu-larly the impact on physiological functions and the hypothalamic-pituitary-adrenal(HPA)axis.TCM,through its multi-component and multi-target approach,can effectively regulate the function of the HPA axis,thereby improving high-altitude stress responses.However,current research still presents the following shortcomings.Firstly,although the introduction of multi-omics technologies offers novel meth-ods to elucidate the mechanisms of TCM,how to effectively integrate data from different levels remains a significant challenge in practi-cal application.Secondly,the broader clinical application of TCM requires substantial evidence-based medical support to verify its effi-cacy and safety.Therefore,future efforts should focus on effectively integrating multi-level data to clarify the mechanisms of TCM,con-ducting high-quality clinical studies to provide evidence-based medical support,and combining modern medical research methods and technologies to deeply investigate the specific mechanisms through which TCM regulates the HPA axis.These steps are will be essential to enhance the application value of TCM in the treatment of acute mountain sickness.关键词
急性高原病/下丘脑-垂体-肾上腺轴/应激反应/中医药Key words
acute mountain sickness(AMS)/hypothalamic-pituitary-adrenal axis/stress response/TCM分类
医药卫生引用本文复制引用
蔡超产,赵朝庭..中医药调控下丘脑-垂体-肾上腺轴改善应激反应治疗急性高原病的作用机制[J].河南中医,2026,46(8):1193-1197,5.基金项目
重庆市教育委员会科学技术研究计划项目(KJQN202515116) （KJQN202515116）
重庆市技术创新与应用发展专项面上项目(CSTB2023TIAD-LDX0026) （CSTB2023TIAD-LDX0026）
