辽宁中医药大学学报2026，Vol.28Issue(8)：7-11,5.DOI:10.13194/j.issn.1673-842X.2026.08.002
眼针联合常规针刺治疗失眠伴焦虑抑郁状态临床疗效观察
Clinical Observation on the Efficacy of Eye Acupuncture Combined with Conventional Acupuncture in Treating Insomnia with Anxiety and Depression
摘要
Abstract
Objective To observe the clinical efficacy of eye acupuncture combined with conventional acupuncture in treating insomnia with anxiety and depression and its effect on serum neurotransmitter levels.Methods A total of 123 patients with insomnia and anxiety-depression were randomly divided into a control group(61 cases)and an observation group(62 cases).The control group received conventional acupuncture,while the observation group received additional PENG's eye acupuncture.Both groups were treated for 4 courses.Changes in Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA),Pittsburgh sleep quality index(PSQI),insomnia severity index(ISI)scores,and serum levels of 5-hydroxytryptamine,γ-aminobutyric acid,norepinephrine,and dopamine were compared before and after treatment.Results After treatment,HAMD,HAMA,PSQI,and ISI scores decreased in both groups(P<0.05),with greater reductions in the observation group(P<0.05).Serum levels of 5-HT and GABA increased,while NE and DA decreased in both groups(P<0.05),with more pronounced changes in the observation group(P<0.05).Conclusion Eye acupuncture combined with conventional acupuncture can significantly improve clinical symptoms in patients with insomnia and anxiety-depression,possibly through regulating serum levels of 5-HT,GABA,NE,and DA.关键词
眼针/针刺/失眠/焦虑抑郁/临床疗效Key words
eye acupuncture/acupuncture/insomnia/anxiety and depression/clinical efficacy分类
医药卫生引用本文复制引用
肖海涛,孟庆媛,唐辉,张宏,兰明月,刘丹..眼针联合常规针刺治疗失眠伴焦虑抑郁状态临床疗效观察[J].辽宁中医药大学学报,2026,28(8):7-11,5.基金项目
黑龙江省中医药科研项目(ZHY2024-002) （ZHY2024-002）
黑龙江省自然科学基金项目(PL2025H263) （PL2025H263）
