辽宁中医药大学学报2026，Vol.28Issue(8)：55-59,5.DOI:10.13194/j.issn.1673-842X.2026.08.010
茯苓治疗高尿酸血症及痛风的药理作用与机制研究
Research on the Pharmacological Effects and Mechanisms of Fuling(Poria)in the Treatment of Hyperuricemia and Gout
摘要
Abstract
Hyperuricemia and gout,as prevalent metabolic disorders,are increasingly affecting global populations and posing significant threats to human health.While Western medicine offers effective symptomatic control,long-term use is often accompanied by adverse effects such as hepatorenal impairment and gastrointestinal reactions,along with poor patient compliance.Fuling(Poria),a traditional Chinese medicine,is renowned for its diuretic,dampness-eliminating,spleen-invigorating,and mind-calming properties.Recent pharmacological studies have revealed that Fuling(Poria)exhibits multi-component,multi-target,and multi-pathway characteristics in the treatment of hyperuricemia and gout.This article systematically reviews the research progress on the modern pharmacological effects and underlying mechanisms of Fuling(Poria)in treating hyperuricemia and gout,with emphasis on its roles in inhibiting uric acid production,promoting uric acid excretion,exerting anti-inflammatory and analgesic effects,protecting renal function,and regulating gut microbiota.Furthermore,this review delves into the theoretical basis of Fuling(Poria)in treating hyperuricemia and gout from the perspective of traditional Chinese medicine theory,providing a more comprehensive theoretical foundation for its clinical application.This article aims to integrate existing research findings to highlight the unique advantages of Fuling(Poria)as a multi-target integrative regulator,thereby offering valuable references for its further investigation and clinical use in the management of hyperuricemia and gout.关键词
茯苓/高尿酸血症/痛风/作用机制/现代药理/中医理论Key words
Fuling(Poria)/hyperuricemia/gout/mechanism of action/modern pharmacology/traditional Chinese medicine theory分类
医药卫生引用本文复制引用
梁翠,王振刚,肖琪琳,蓝锦绣,刘光诺,刘诗娟..茯苓治疗高尿酸血症及痛风的药理作用与机制研究[J].辽宁中医药大学学报,2026,28(8):55-59,5.基金项目
国家自然科学基金项目(82060804) （82060804）
广西自然科学基金项目(2024GXNSFAA010285,2025GXNSFAA069339) （2024GXNSFAA010285,2025GXNSFAA069339）
广西中医药适宜技术开发与推广项目(GZSY23-23) （GZSY23-23）
