陕西中医2026，Vol.47Issue(8)：1046-1051,6.DOI:10.3969/j.issn.1000-7369.2026.08.006
心血宁片治疗急性缺血性脑卒中合并高血压1级及高脂血症疗效研究
Efficacy study on Xinxuening tablets in treatment of acute ischemic stroke complicated with grade 1 hypertension and hyperlipidemia
摘要
Abstract
Objective:To explore effects of Xinxuening tablets in treatment of acute ischemic stroke complicated with grade 1 hypertension and hyperlipidemia.Methods:89 patients with acute ischemic stroke complicated by grade 1 hypertension and hyperlipidemia were randomly divided into control group(45 cases)and treatment group(44 ca-ses).The control group were given oral Levamlodipine Besylate tablets and atorvastatin calcium tablets.The treat-ment group received oral Xinxuening tablets in addition to the control group's regimen.Both groups were treated for 8 weeks.Compare the changes in 24-hour systolic blood pressure(24hSBP),24-hour diastolic blood pressure(24hDBP),serum low-density lipoprotein cholesterol(LDL-C),total cholesterol(TC),high-density lipoprotein cho-lesterol(HDL-C),and triglyceride(TG)levels between the two groups before and after treatment.Additionally,compare the changes in the syndrome elements of ischemic stroke-blood stasis,phlegm-dampness,internal fire,Yin deficiency,Qi deficiency and traditional Chinese medicine symptom scores between the two groups before and after treatment.Results:After treatment,24hSBP,24hDBP,and serum LDL-C decreased in both groups compared to before treatment,and the reduction magnitudes in the treatment group were superior to those in the control group(P＜0.05).After treatment,the syndrome scores for phlegm-dampness,blood stasis,and internal fire,as well as total TCM symptom scores decreased in both groups compared to before treatment.The treatment group achieved signifi-cantly greater reductions in blood stasis syndrome score and total TCM symptom score than the control group(P＜0.05).Conclusion:Xinxuening tablets were effective in treating acute ischemic stroke complicated with grade 1 hyper-tension and hyperlipidemia.They could significantly improve stroke blood stasis syndrome scores and TCM symptom scores in these patients,control blood pressure levels,reduce blood lipids,and enhance treatment efficacy,warranting further clinical research and discussion.关键词
急性缺血性卒中/高血压病1级/高脂血症/心血宁片/24小时血压/低密度脂蛋白/缺血性中风中医证候积分Key words
Acute ischemic stroke/Grade 1 hypertension/Hyperlipidemia/Xinxuening tablets/24-hour blood pressure/Low-density lipoprotein cholesterol/Ischemic stroke TCM syndrome score分类
医药卫生引用本文复制引用
陈玉娇,张家成,孙静,李翔宇,张根明..心血宁片治疗急性缺血性脑卒中合并高血压1级及高脂血症疗效研究[J].陕西中医,2026,47(8):1046-1051,6.基金项目
国家重点研发计划课题(2019YFC1712003) （2019YFC1712003）
吴阶平医学基金会临床科研专项基金资助项目(320.6750.2022-25-13) （320.6750.2022-25-13）
